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Adult male hypogonadism (HG) is the most common form of diminished gonadal activity in men. Most clinicians prescribe testosterone replacement therapy to treat primary HG, but other therapeutic options are available.
Renal clearance can be significantly elevated in the critically ill. Treating these patients with renally cleared drugs can present a problem. Drugs—whisked through the body with greater than expected efficiency, a process called augmented renal clearance (ARC)—reach only suboptimal levels and, consequently, patients experience no improvement or actual clinical decline. ARC is often associated with elevated urinary creatinine clearance.
In March 2014, the Society of Surgical Oncology Susan G. Komen for the Cure Symposium focused on the literature on the epidemiology, molecular pathology, and therapy considerations of triple-negative breast cancer. The Annals of Surgical Oncology has published a summary of this work ahead of print.
Since children diagnosed with autism spectrum disorders (ASD) may also have epileptic disorders, physicians usually want electroencephalograms (EEGs) of their brains.One sign of autism is staring spells. That can also be a form of epilepsy, an absence seizure.But an Australian study of children referred for these episodes showed EEGs offer little diagnostic benefit.
Abandonment alters children's brain tissue.Children who experienced extreme neglect showed physical changes in the white matter of their brains, a Boston team found.Writing in JAMA Pediatrics Johanna Bick PhD and colleagues at Boston Children’s Hospital reported on the Bucharest Early Intervention Project.
Finding brain beta amyloid is usefull in assessing Alzheimer's Disease. In a report in JAMA Neurology, Craig Curtis, MD and colleagues report on a multicenter PET imaging study on terminally ill dementia patients using flutemetamol injections tagged with radioactive fluorine 18. In cases where autopsy was later possible, the team assessed how accurate the tests had been in diagnosing Alzheimer's.
Isolated systolic hypertension (ISH) in young and middle-aged adults is on the rise. A study in the Journal of the American College of Cardiology found that ISH puts these patients at higher relative risk for heart disease and mortality than their peers with normal blood pressure. That raises the question of whether these younger ISH patients should be getting drug therapy.
As a blizzard predicted to break snowfall records bears down upon the Northeast, hospitals and physicians are shifting into disaster-planning mode. With the worst of the blizzard expected to hit coastal New England, Mass. Gov. Charlie Baker has declared a state of emergency and instituted a travel ban that will take effect at midnight. , per Boston.com. Shriner’s Hospital in Boston canceled elective procedures and clinic visits. New Jersey Gov. Chris Christie declared a state of emergency at noon Monday, closing state offices and urging motorists to stay off the roads. In a news conference this afternoon, he said the state’s emergency workers and transportation department can handle the storm.
Researchers have developed a safer method for testing d-dimer values in patients over the age of 50 years, according to research published in the journal CHEST.