HCPLive Network

Any Amount of Smoking Increases Risk of Sudden Cardiac Death in Women

 
WEDNESDAY, Dec. 12 (HealthDay News) -- For women without coronary heart disease (CHD) at baseline, smoking, even in small quantities, is associated with a significantly increased risk of sudden cardiac death (SCD), according to research published online Dec. 11 in Circulation: Arrhythmia and Electrophysiology.

Roopinder K. Sandhu, M.D., M.P.H., from the University of Alberta in Edmonton, Canada, and colleagues prospectively examined the correlation between cigarette smoking and smoking cessation on the risk of SCD among 101,018 women from the Nurses' Health Study without CHD, stroke, or cancer at baseline in 1980.

During 30 years of follow-up, the researchers identified 351 SCD events. After controlling for coronary risk factors, current smokers had a significant 2.44-fold increased risk of SCD compared with never smokers. Among current smokers, the quantity of cigarettes smoked daily and smoking duration were significantly linearly linked to SCD risk in multivariate analysis. The risk of SCD was significantly increased even with small-to-moderate amounts of cigarette consumption (one to 14 per day; 1.84-fold increased risk) and with every five years of continued smoking (hazard ratio, 1.08). After quitting, there was a linear decrease in the risk of SCD over time, and after 20 years of cessation, the risk was equivalent to that of a never smoker.

"A dose-dependent relationship between smoking and SCD was observed, and even small-to-moderate quantities of daily smoking were associated with SCD risk," the authors write. "Efforts to prevent SCD among women should consider aggressive strategies for smoking cessation among all women."
 

Abstract
Full Text (subscription or payment may be required)

 
Copyright © 2012 HealthDay. All rights reserved.
 
 

Further Reading
New questions about the risks of flying and the responsibilities of airlines have followed reports of anaphylaxis cases on two international flights in less than a month.
Trulicity (dulaglutide) is a once-weekly subcutaneous injection to improve glycemic control, along with diet and exercise, in adults with type 2 diabetes.
While there is room for improvement in the timeliness of emergency department care, pressure to comply with length of stay measures may have unintended consequences, according to two research letters published online Sept. 15 in JAMA Internal Medicine.
No significant difference in outcomes is observed between the use of ultrasonography or computed tomography for suspected nephrolithiasis, according to research published in the Sept. 18 issue of the New England Journal of Medicine.
Reports suggest that combination therapy with the drug afamelanotide and narrowband ultraviolet-B ray (NB UVB) phototherapy is safe and effective for restoring skin pigmentation in patients with vitiligo, a skin disease resulting from dead melanin-producing cells with no current cure.
The rate of major adverse cardiovascular events is higher in patients with diabetes mellitus and multivessel coronary artery disease treated with insulin versus those not treated with insulin, according to a study published in the Sept. 23 issue of the Journal of the American College of Cardiology.
For patients undergoing lumbar spine surgery, Clostridium difficile infection is associated with longer, more expensive hospital stays, and increased mortality, according to a study published in the Sept. 1 issue of Spine.
More Reading