HCPLive Network

BCIS Myocardial Jeopardy Score Predicts Post-PCI Death

 
FRIDAY, Jan. 18 (HealthDay News) -- The British Cardiovascular Intervention Society myocardial jeopardy score (BCIS-JS) predicts mortality after percutaneous coronary intervention (PCI), according to research published in the Jan. 15 issue of The American Journal of Cardiology.

Kalpa De Silva, M.B.B.S., of King's College London, and colleagues conducted a retrospective study involving 660 patients who underwent PCI with previous left ventricular function assessment. Of these, 221 patients had previously undergone coronary artery bypass grafting (CABG). Blinded observers calculated the BCIS-JS before (BCIS-JSPRE) and after (BCIS-JSPOST) PCI, and the extent of revascularization was quantified using the revascularization index (RI; RI = [BCIS-JSPRE − BCIS-JSPOST]/BCIS-JSPRE).

The researchers found that both BCIS-JSPRE and BCISJSPOST scores were directly related to all-cause mortality (hazard ratios [HRs], 2.96 and 4.02, respectively). Other independent predictors of mortality included having a RI of less than 0.67 (HR, 1.99), left ventricular dysfunction (HR, 2.03), and renal impairment (HR, 3.75), in multivariate analysis.

"The present findings have demonstrated that the BCIS-JS has prognostic significance in a contemporary cohort of patients undergoing PCI. Higher BCIS-JSPRE and BCIS-JSPOST scores are associated with increased mortality and the BCIS-JS-derived RI is an independent predictor of mortality," the authors write. "Our findings confirm that the BCIS-JS is a highly reproducible, valid angiographic scoring tool and supports its use in risk stratification and guiding PCI in patients with coronary artery disease, including patients who have undergone previous CABG."
 

Abstract
Full Text (subscription or payment may be required)


Copyright © 2013 HealthDay. All rights reserved.
 
 

Further Reading
Researchers assessed the effect of seizure status and severity, medication use, mental health indicators, parental support, and other factors on self-reported quality of life in children with epilepsy.
A group of international researchers led by Luosheng Li, MD, of the Rolf Luft Research Center for Diabetes and Endocrinology at the Karolinska Institutet, Karolinska University Hospital in Stockholm, Sweden, recently demonstrated that age-dependent decline in insulin secretion (and thus glucose homeostasis) from the beta cell in experimental mice models is associated with subtle changes in Ca2+ dynamics.
For patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD), the right treatment can make a world of difference in the management of their condition. A recent study looked at how effective inhaled budesonide and systemic methylprednisolone can be for those patients.
More Reading