HCPLive Network

Data Suggest Depression Doesn't Precede Impaired Cognition

 
MONDAY, Jan. 7 (HealthDay News) -- Among older adults, depression correlates with prevalent mild cognitive impairment (MCI) and progression to dementia, but not with incident MCI, according to a study published online Dec. 31 in JAMA Neurology.

To examine the correlation of late-life depression with MCI and dementia, Edo Richard, M.D., Ph.D., from the University of Amsterdam, and colleagues conducted a cohort study involving 2,160 community-dwelling Medicare recipients, aged 65 years or older, from New York City.

The researchers found that the likelihood of prevalent MCI (odds ratio, 1.4) and dementia (odds ratio, 2.2) were significantly elevated with baseline depression. Depression at baseline correlated with a significantly elevated risk of incident dementia (hazard ratio [HR], 1.7), but not incident MCI (HR, 0.9; 95 percent confidence interval, 0.7 to 1.2). The risk of progression to dementia, especially vascular dementia, but not Alzheimer's disease, was elevated for those with MCI and coexisting depression at baseline (HR, 2.0 for dementia and 4.3 for vascular dementia).

"The association of depression with prevalent MCI and with progression from MCI to dementia, but not with incident MCI, suggests that depression accompanies cognitive impairment but does not precede it," the authors write.
 

Abstract
Full Text (subscription or payment may be required)

 
Copyright © 2013 HealthDay. All rights reserved.
 
 

Further Reading
App will help patients with diabetes log their hypoglycemic events and achieve better control of these events by becoming more aware of preceding signs and symptoms.
Provocative research raises the question of whether we should we look at Alzheimer’s disease as “type 3 diabetes.”
Presentation at CMHC 2014 provides updates on emerging classes of diabetes treatment, including preliminary data from current clinical trials.
In remarks delivered at the American Academy of Family Physicians 2014 Assembly, HHS Secretary Sylvia Mathews Burwell spoke about the ongoing response to the Ebola outbreak, improving health care delivery, the Affordable Care Act, and the Transforming Clinical Practice Initiative.
Seniors who wear their dentures when they sleep are at increased risk for pneumonia, according to a study published online Oct. 7 in the Journal of Dental Research.
New York and New Jersey health officials announced today that all health care workers returning from caring for patients in Ebola hot zones in West Africa will have to go into quarantine for 21 days. The new policy is stricter than the current one recommended by the US Centers for Disease Control and Prevention that calls for health monitoring for 21 days. It was that policy that allowed Craig Spencer, MD to be out and about a day before he was diagnosed with Ebola Thursday and rushed to city-run Bellevue Hospital Center in Manhattan.
A pattern of sleep disturbance is a risk factor for depression and suicide and also increases the risk of cancer, infection, hypertension, weight gain, heart disease, diabetes, inflammation, osteoporosis, chronic pain, and arrhythmias. It can also have a significant negative impact on cognition and creativity.
More Reading