Shai Efrati, M.D., from the Assaf Harofeh Medical Center in Zerifin, Israel, and colleagues treated 74 patients who had suffered a stroke six to 36 months earlier with 40 sessions of HBOT over two months (five days a week, 90 minutes, 100 percent oxygen), either immediately or after a two-month period of no treatment.
The researchers found that HBOT significantly improved neurological function and quality of life, while no improvement was observed during the two-month untreated period. Improvements in brain metabolism, as determined by single photon emission computed tomography, correlated with clinical improvement. Brain activity improved in areas that contained live cells but low activity.