HCPLive Network

Novel Racial/Ethnic Differences Found in Diabetic Kidney Disease

 
MONDAY, Jan. 14 (HealthDay News) -- Rates of proteinuric and nonproteinuric diabetic kidney disease (DKD) vary significantly across racial/ethnic groups, according to a study published online Dec. 13 in Diabetes Care.

To assess racial/ethnic differences in the prevalence of DKD, Vivek Bhalla, M.D., from the Stanford University School of Medicine in California, and colleagues reviewed electronic health records (2008 to 2010) for 15,683 persons of non-Hispanic white (NHW), Asian (Asian Indian, Chinese, and Filipino), Hispanic, and non-Hispanic black (NHB) race/ethnicity with type 2 diabetes and without previous history of kidney disease.

The researchers found that, compared with NHWs, racial/ethnic minorities had higher rates of proteinuric DKD (24.8 to 37.9 versus 24.8 percent) and lower rates of nonproteinuric DKD (6.3 to 9.8 versus 11.7 percent). Compared with NHWs, the odds of proteinuric DKD were significantly increased for Chinese (odds ratios [ORs], 1.39 for women and 1.56 for men), Filipinos (ORs, 1.57 for women and 1.85 for men), Hispanics (ORs, 1.46 for women and 1.34 for men), and NHBs (OR, 1.50 for women), after adjustment. In contrast, compared with NHWs, significantly lower odds of nonproteinuric DKD were observed among Chinese, Hispanic, and NHB women and Hispanic men.

"In summary, rates of proteinuric and nonproteinuric DKD vary significantly across racial/ethnic groups," the authors write. "Additional prospective studies are needed to confirm these associations, as such studies could lead to improved public health surveillance of diabetes complications within diverse communities."
 

Abstract
Full Text (subscription or payment may be required)

 
Copyright © 2013 HealthDay. All rights reserved.
 
 

Further Reading
The correlation between lower income and albuminuria is stronger in blacks than whites, and may be one determinant of racial disparities in albuminuria, according to a study published in the November issue of the American Journal of Kidney Diseases.
Study results reported at Kidney Week 2012 reveal that patients with early-stage CKD fare better in the public health system, which also appears to produce fewer racial and ethnic health disparities in care delivered to this population.
Evidence-based strategies can alleviate gaps in providers' knowledge of chronic kidney disease and diabetes in underserved patient populations.
Increasing numbers of people are on kidney transplant waiting lists. However, the number of potential living donors may shrink as more Americans qualify as pre-diabetic, making them less than ideal donor candidates.
Early diagnosis by primary care physicians and aggressive treatment are essential to slowing the epidemic of kidney and cardiovascular disease.
A diet rich in highly alkaline fruits and vegetables helps reduce a marker of kidney injury and preserve kidney function in patients with chronic kidney disease.
Results from the TEMPO trial presented at Kidney Week 2012 show that treatment with tolvaptan slowed the increase in total kidney volume and the decline in kidney function in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD).
More Reading