HCPLive Network

Prenatal Vitamin C Cuts Wheeze in Babies of Smokers

MONDAY, May 6 (HealthDay News) -- For women who smoke, vitamin C supplementation during pregnancy is associated with reduced incidence of wheezing in their offspring through the age of 1 year, according to a study presented at the annual meeting of the Pediatric Academic Societies, held from May 4 to 7 in Washington, DC.

Cindy T. McEvoy, MD, from the Oregon Health & Science University, in Portland, and colleagues examined the impact of supplemental daily vitamin C during pregnancy on the incidence of wheezing within the first year of life. The infants of 76 smokers randomized to vitamin C, the infants of 83 smokers randomized to placebo, and the infants of 76 nonsmokers were assessed at delivery. Ninety-two percent were followed through age 1.

The researchers found that significantly fewer infants of vitamin-C treated versus placebo-treated smokers had at least one episode of wheezing (21 versus 40 percent; adjusted P = 0.019) and fewer infants received medication for wheezing (13 versus 22 percent; adjusted P = 0.14). The incidence of wheezing was significantly lower for those randomized to vitamin C versus placebo for infants of pregnant smokers homozygous or heterozygous for the rs16969968 risk allele (14 versus 48 percent; P = 0.01).

"Vitamin C is a simple, safe, and inexpensive treatment that may decrease the impact of smoking during pregnancy on childhood respiratory health," McEvoy said in a statement. "Though the lung function of all babies born to smokers in our study was improved by supplemental vitamin C, our preliminary data suggest that vitamin C appeared to help those babies at the greatest risk of harm during their development from their mother's smoking in pregnancy."

Press Release
More Information

Copyright © 2013 HealthDay. All rights reserved.

Further Reading
There is no link between vaccines and increased risk of multiple sclerosis or other acquired central nervous system demyelinating syndromes, according to a study published online Oct. 20 in JAMA Neurology.
Researchers at Hong Kong University and the Wellcome Trust Sanger Institute have identified a link between the influenza A viruses’ genetic diversity and severity of the infection.
Carol Burke, MD, FACG, FASGE, talks about her phase-3 placebo-controlled trial of Celecoxib in pediatric subjects with familial adenomatous polyposis (FAP) at the 2014 ACG Annual Meeting in Philadelphia, PA.
Carol Burke, MD, FACG, FASGE, discusses pediatric familial adenomatous polyposis (FAP) and colorectal cancer at the 2014 ACG Annual Scientific Meeting in Philadelphia, PA.
The immune system is the new focus of much work on traumatic brain injury (TBI). In a challenge to the paradigm that the blood brain barrier prevents harmful leukocytes from entering the brain, a Texas team tried to neutralize the impact of these cells. Peripheral lymphocytes are activated after TBI. They may then act as potential antigen presenting cells and get into the brain, causing cells there to degenerate.
Black women undergoing in vitro fertilization are only about half as likely as white women to become pregnant, and the racial disparity persists even when donor eggs are used. These findings are being presented at the annual meeting of the American Society for Reproductive Medicine, held from Oct. 18 to 22 in Honolulu.
Hospital conversion to for-profit status is associated with improvements in financial margins, but has no effect on process quality metrics or mortality rates, according to a study published in the Oct. 22/29 issue of the Journal of the American Medical Association
More Reading