HCPLive Network

Researchers Identify Features of Serious Pertussis Progression in Infants

 
FRIDAY, Jan. 18 (HealthDay News) -- Rapidly rising white blood cell (WBC) counts and high heart rates and respiratory rates may indicate more serious pertussis progression in infants, according to research published online Jan. 10 in the Journal of the Pediatric Infectious Diseases Society.

Erin L. Murray, Ph.D., from the California Department of Public Health in Richmond, and colleagues reviewed medical records for 31 infants who were ≤90 days of age and hospitalized for pertussis in five Southern California pediatric intensive care units (from Sept. 1, 2009, through June 30, 2011) to obtain demographic and clinical information.

The researchers found that eight of the infants had more severe infections, six had pulmonary hypertension, and four died. Compared with less severe illness, more severe illness was characterized by WBC counts exceeding 30,000, heart rates exceeding 170, and respiratory rates exceeding 70 more rapidly after cough onset.

Our data suggest that a predictor of more severe Bordetella pertussis disease in young infants is an elevated and rapidly rising WBC count, making early and serial WBC count determinations critical to the evaluation of all infants with suspected or proven pertussis," the authors write. "Furthermore, close monitoring of heart and respiratory rates is imperative because these were demonstrated to correlate with more severe disease progression."
 

Abstract
Full Text (subscription or payment may be required)


Copyright © 2013 HealthDay. All rights reserved.
 

Further Reading
In remarks delivered at the American Academy of Family Physicians 2014 Assembly, HHS Secretary Sylvia Mathews Burwell spoke about the ongoing response to the Ebola outbreak, improving health care delivery, the Affordable Care Act, and the Transforming Clinical Practice Initiative.
Seniors who wear their dentures when they sleep are at increased risk for pneumonia, according to a study published online Oct. 7 in the Journal of Dental Research.
New York and New Jersey health officials announced today that all health care workers returning from caring for patients in Ebola hot zones in West Africa will have to go into quarantine for 21 days. The new policy is stricter than the current one recommended by the US Centers for Disease Control and Prevention that calls for health monitoring for 21 days. It was that policy that allowed Craig Spencer, MD to be out and about a day before he was diagnosed with Ebola Thursday and rushed to city-run Bellevue Hospital Center in Manhattan.
A pattern of sleep disturbance is a risk factor for depression and suicide and also increases the risk of cancer, infection, hypertension, weight gain, heart disease, diabetes, inflammation, osteoporosis, chronic pain, and arrhythmias. It can also have a significant negative impact on cognition and creativity.
For stroke survivors, annual direct costs are comparable at 10 years and between 3 to 5 years for ischemic stroke but are higher at 10 years after hemorrhagic stroke, according to a study published online Oct. 23 in Stroke.
There is little variation in risk-adjusted hospital readmission rates after colorectal surgery, according to a study published online Oct. 22 in JAMA Surgery.
Cardiovascular disease is a long-term complication of type 1 diabetes mellitus, and more attention toward management of its associated risk factors and modifiers is urged in a scientific statement published in the October issue of Diabetes Care.
More Reading