HCPLive Network

Researchers Identify Features of Serious Pertussis Progression in Infants

 
FRIDAY, Jan. 18 (HealthDay News) -- Rapidly rising white blood cell (WBC) counts and high heart rates and respiratory rates may indicate more serious pertussis progression in infants, according to research published online Jan. 10 in the Journal of the Pediatric Infectious Diseases Society.

Erin L. Murray, Ph.D., from the California Department of Public Health in Richmond, and colleagues reviewed medical records for 31 infants who were ≤90 days of age and hospitalized for pertussis in five Southern California pediatric intensive care units (from Sept. 1, 2009, through June 30, 2011) to obtain demographic and clinical information.

The researchers found that eight of the infants had more severe infections, six had pulmonary hypertension, and four died. Compared with less severe illness, more severe illness was characterized by WBC counts exceeding 30,000, heart rates exceeding 170, and respiratory rates exceeding 70 more rapidly after cough onset.

Our data suggest that a predictor of more severe Bordetella pertussis disease in young infants is an elevated and rapidly rising WBC count, making early and serial WBC count determinations critical to the evaluation of all infants with suspected or proven pertussis," the authors write. "Furthermore, close monitoring of heart and respiratory rates is imperative because these were demonstrated to correlate with more severe disease progression."
 

Abstract
Full Text (subscription or payment may be required)


Copyright © 2013 HealthDay. All rights reserved.
 

Further Reading
John Saltzman, MD, Discusses the gastrointestinal tract and its part in the functioning of the body.
Type 2 diabetes occurs at roughly the same prevalence in men and women. Despite the similar prevalence in the sexes, women who develop diabetes feel the effect of its complications disproportionately.
Research presented at the European League Against Rheumatism’s Annual Meeting indicates comorbid diabetes may be linked to increased osteoarthritis pain.
Analysis of a dozen phase III trials indicates that patients with atrial fibrillation face significantly less risk of major, fatal, and intracranial bleeding if they take target-specific oral anticoagulants rather than vitamin K antagonists.
Calculation and interpretation of the anion gap is extremely useful in the evaluation and treatment of the patient with metabolic acidosis. In this installment, we look at case examples involving patients with multiple sclerosis and urosepsis; COPD, diabetes, and renal failure; and type 1 diabetes.
The US Department of Homeland Security (DHS) will begin limiting the airports through which travelers from Ebola-stricken countries may enter the US. Starting tomorrow, all these passengers will be forced to fly through 5 US airports: JFK International in New York, Newark Liberty International in Newark, NJ, Washington Dulles International in Dulles, VA, Hartsfield-Jackson International in Atlanta, GA, and Chicago O’Hare International in Chicago, Ill.
Medications commonly used to treat Parkinson's disease may raise the risk of impulse control disorders such as compulsive gambling, compulsive shopping, and/or hypersexuality, according to a new review published online Oct. 20 in JAMA Internal Medicine.
More Reading