HCPLive Network

Switching to Vegetable Fat May Cut Prostate Cancer Death Risk

TUESDAY, June 11 (HealthDay News) -- For men with non-metastatic prostate cancer, the risks of lethal prostate cancer and all-cause mortality are significantly reduced with replacement of carbohydrates by vegetable fats, according to a study published online June 10 in JAMA Internal Medicine.

Erin L. Richman, ScD, from the University of California in San Francisco, and colleagues conducted a prospective study involving 4,577 men with non-metastatic prostate cancer to examine the correlation between post-diagnostic fat intake and outcomes (lethal prostate cancer and all-cause mortality).

During a median follow-up of 8.4 years, the researchers identified 315 lethal cancer events (distant metastases or prostate cancer-specific death) and 1,064 deaths. The risks of lethal prostate cancer and all-cause mortality were significantly reduced with replacement of 10 percent of energy intake from carbohydrate with vegetable fat (hazard ratios, 0.71 and 0.74, respectively). No association was seen with other fats and lethal prostate cancer. Higher all-cause mortality was seen with an increase in saturated and trans fats after diagnosis (replacement of 5 and 1 percent of energy from carbohydrates, respectively), with hazard ratios of 1.30 and 1.25, respectively.

"In conclusion, among men with non-metastatic prostate cancer, replacing carbohydrates and animal fat with vegetable fat may reduce the risk of all-cause mortality," the authors write. "The potential benefit of vegetable fat consumption for prostate cancer-specific outcomes merits further research."

Abstract
Full Text (subscription or payment may be required)

Copyright © 2013 HealthDay. All rights reserved.

Further Reading
In remarks delivered at the American Academy of Family Physicians 2014 Assembly, HHS Secretary Sylvia Mathews Burwell spoke about the ongoing response to the Ebola outbreak, improving health care delivery, the Affordable Care Act, and the Transforming Clinical Practice Initiative.
Seniors who wear their dentures when they sleep are at increased risk for pneumonia, according to a study published online Oct. 7 in the Journal of Dental Research.
New York and New Jersey health officials announced today that all health care workers returning from caring for patients in Ebola hot zones in West Africa will have to go into quarantine for 21 days. The new policy is stricter than the current one recommended by the US Centers for Disease Control and Prevention that calls for health monitoring for 21 days. It was that policy that allowed Craig Spencer, MD to be out and about a day before he was diagnosed with Ebola Thursday and rushed to city-run Bellevue Hospital Center in Manhattan.
A pattern of sleep disturbance is a risk factor for depression and suicide and also increases the risk of cancer, infection, hypertension, weight gain, heart disease, diabetes, inflammation, osteoporosis, chronic pain, and arrhythmias. It can also have a significant negative impact on cognition and creativity.
There is little variation in risk-adjusted hospital readmission rates after colorectal surgery, according to a study published online Oct. 22 in JAMA Surgery.
Cardiovascular disease is a long-term complication of type 1 diabetes mellitus, and more attention toward management of its associated risk factors and modifiers is urged in a scientific statement published in the October issue of Diabetes Care.
For patients with lumbosacral disc herniation, neurophysiological tests together with neuroimaging and clinical examination allow for accurate preoperative assessment of injury, according to a study published in the Oct. 1 issue of Spine.
More Reading