By Andrew J. Roth
Most deaths from breast cancer occur in women who have not been regularly screened and whose tumors are diagnosed at a median age 49 years, confirming the need for the greater use of annual mammography in younger women, according to a recent study that marks the latest episode in the debate over screening guidelines.
By Jane de Lartigue, PhD
The phosphatidylinositol 3-kinase pathway is frequently deregulated in cancer at multiple different points, and has therefore emerged as one of the most deeply explored cell-signaling networks in oncogenic research.
Global health disparities could be reduced considerably by 2035 using an investment framework, according to a report published Dec. 3 in The Lancet.
By Andrew J. Roth
Interventional oncology is an emerging field in cancer care that is intended to complement existing treatment modalities. We sat down with Dan Brown, MD, the new chief of Interventional Oncology at Vanderbilt University Medical Center, to discuss the burgeoning field and its potential effect on cancer care moving forward.
By Jeannette Wick
A retrospective analysis of the association between cancer and diabetes found that patients with type 2 diabetes mellitus (T2DM) are more than 30% more likely to develop cancer than their counterparts who do not have T2DM.
By Kathy Boltz, PhD
The increased cost of new branded oncology drugs continues to receive much negative press. Recent editorials have criticized the high cost of new cancer therapies, and their less than stellar improvements in efficacy, over already existing, lower-cost treatment options. Such critics have argued that little or no correlation between drug efficacies and pricing exists.
By Anna Azvolinsky, PhD
With seven targeted therapies approved for metastatic renal cell carcinoma, researchers and drug developers are now focusing on understanding the best way to sequence these therapies and on identifying predictive biomarkers of response.
By Jill Stein
The addition of albumin-bound paclitaxel (nab-paclitaxel; Abraxane) to standard treatment with gemcitabine significantly lengthens survival in patients with metastatic pancreatic cancer, researchers report.
The US Food and Drug Administration on Monday began the process of regulating compounding pharmacies. Under the Drug Quality and Security Act, signed into law Nov. 27 by President Barack Obama, these pharmacies are being encouraged to register with the FDA. The agency will then classify them as outsourcing pharmacies, enabling them to sell bulk drugs to hospitals and other health care facilities.
For patients with early cancer, a nurse navigator intervention can improve patient experience and reduce problems with care, according to a study published online Nov. 25 in the Journal of Clinical Oncology.
Use of digital breast tomosynthesis, an imaging method that produces three-dimensional reconstructions of the breast, for cancer screening significantly reduces callback rates and increases cancer detection rates compared with digital mammography, according to a study presented at the annual meeting of the Radiological Society of North America, held from Dec. 1 to 6 in Chicago.
Two geriatric screening tools show effectiveness at predicting functional decline and overall survival in an older population with cancer, according to a study published online Nov. 25 in the Journal of Clinical Oncology.
Physician volunteer programs can revive doctors' passion for medicine, according to an article published Nov. 11 in Medical Economics.
By Anas Younes, MD
During the past three decades, our treatment approach to lymphoma has been based on the underlying histological and clinical features of the disease.
By Jill Stein
Both men and women report a significant decline in sexual satisfaction after hematopoietic cell transplantation that is sustained at 3-year follow-up.
By Silas Inman
Ramucirumab, a monoclonal antibody that targets VEGFR-2, significantly prolonged survival in patients with advanced gastric or gastroesophageal junction (GEJ) adenocarcinoma following progression on first-line therapy, according to results from the phase III REGARD study published in The Lancet.
The top five dermatology-related issues that physicians and patients should question have been released by the American Academy of Dermatology (AAD) as part of the Choosing Wisely campaign.
Women from BRCA2 families who do not carry a mutation in the BRCA2 breast cancer susceptibility gene still have a nearly five-fold higher risk of developing breast cancer.
By Andrew D. Smith
Quest Diagnostics, a business founded 46 years ago in a medical resident’s two-room apartment, has parlayed the exponential subsequent growth in medical testing into an operation worth $8.5 billion.
Small medical practices may not need to offer their employees health insurance, although there may be advantages to doing so, according to an article published Nov. 10 in Medical Economics.