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HIV AIDS

The effects of trials to improve medication adherence are inconsistent, with few studies of the highest quality demonstrating improvement in both adherence and clinical outcome, according to a review published online Nov. 20 in The Cochrane Library.
Market forces are dramatically driving up the cost of some generic drugs, prompting US investigations into the pricing of what should be cheap alternatives to brand-name medications.
A recent study led by researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine has shown that aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) protect against the development of colorectal cancer through cell suicide pathway induction in intestinal stem cells that carry a certain mutated gene.
A national clinical trial has found non-efavirenz antiretroviral therapy effective as a first-line treatment, which is good news for patients with HIV who are ineligible to use the common drug.
Of the more than 1.5 million patients who received hospice care in the United States in 2013, one-third died within one week, according to a new report from the National Hospice and Palliative Care Organization.
Important points are often missed when doctors have end-of-life discussions with patients and their families, according to a study published online Nov. 3 in CMAJ, the journal of the Canadian Medical Association.
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