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Major Depressive Disorder

Exhaustion, depersonalization, and perceived lack of personal accomplishment—these are the signs of burnout, a syndrome that decreases efficacy at work.
This systematic review and meta-analysis hope to determine the influence of non-steroidal anti-inflammatory agent use on depressive symptoms and in those with depression.
The symptoms of depression were reduced in mice models which had high levels of PGC-1a1 in their skeletal muscle.
A study presented at the American Heart Association (AHA) Scientific Sessions 2014 reported home exercise could potentially alleviate feelings of hopelessness in people afflicted with coronary heart disease.
Thyroid dysfunction causes many well-recognized changes at the level of the brain, and most are reversible with treatment. Patients who have hypothyroidism often have other neuropsychiatric comorbidities, including affective disorders, depression, cognitive function loss, anxiety, or irritability.
Emotional response to stress can contribute to depressive symptoms, suggests a study published in PNAS.
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