The MD Magazine Gout condition center provides clinical news and articles, information about upcoming conferences and meetings, updated clinical trial listings, and other resources.

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New Drug Deemed Effective for Opioid-Induced Constipation
With 259 million painkiller prescriptions written in 2012 alone, according to the Centers for Disease Control and Prevention (CDC), one of the most common side effects experienced by patients being treated for chronic pain is opioid-induced constipation (OIC).
About 8% of patients with systemic lupus erythematosus (SLE) have pulmonary hypertension (PH), and serum uric acid (UA) has reasonable accuracy for predicting PH, according to a study published in the June issue of the International Journal of Rheumatic Diseases.

A gout medication did not show significant statistical benefit in lowering flares associated with the condition.
According to Theodore R. Fields, MD, studies show that only about 20 percent of patients with gout receive guideline-compliant treatment. A large percentage of patients who do receive proper medications do not adequately adhere to their treatment regimen, leading to poor outcomes.
In this segment, Theodore R. Fields, MD, talks about the benefits of early treatment in patients with gout and also discusses the impact comorbid conditions can have on the course of the disease and treatment outcomes.
Researchers will evaluate the safety, pharmacodynamic profile, and immunogenicity of pegsiticase for the treatment of painful refractory and tophaceous gout.
ABCG2 Q141K (rs2231142) is associated with gout risk, and gender and ethnicity affect the association, according to a meta-analysis published in the May issue of the International Journal of Rheumatic Diseases.

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