HCPLive Network

Demystifying Colorectal Hereditary Syndromes

 
Medical and surgical strategies for gastrointestinal cancer surveillance were discussed by a researcher from Puerto Rico at a presentation given this week during a joint conference of the American Gastroenterological Association and the American Society for Gastrointestinal Endoscopy in Coronado, California.
 
About one in 25 people in the United States will develop colorectal cancer, said Marcia Cruz-Correa, MD, an associate professor of medicine and biochemistry at the University of Puerto Rico at San Juan. The risk increases to about 15 to 20 percent when a family member has the disease, she said.
 
People with hereditary colorectal syndromes such as Lynch syndrome, adenomatous polyposis, and hamartomatous polyposis have a much higher likelihood of developing colorectal cancer.
 
Cancer in people with Lynch syndrome usually develops before the age of 50, with the tumors on the right side of the colon about 60 percent of the time. “If someone has Lynch syndrome by age 50, 25 percent of them will already have colorectal cancer, compared to less than 5 percent in the US population,” said Cruz-Correa.


Further Reading
Study results show many patients with chronic obstructive pulmonary disease (COPD) may experience cognitive deterioration that becomes more severe as their COPD worsens.
Resistant hypertension is common among patients with type 2 diabetes, and is strongly associated with microvascular disease.
Schools could do more to ensure that children with Autism Spectrum Disorders (ASD) are getting adequate exercise, a team of Oregon State University researchers found. Writing in Autism Research and Treatment Kiley Tyler and colleagues reported on their study measuring the physical fitness of children with ASD. The study was done at OSU in Corvallis, OR, where Tyler is a doctoral student in exercise and sport science.
In this installment, we look at underlying causes of metabolic acidosis, approaches for evaluating patients with suspected metabolic acidosis, and why measurement of the anion gap is of great usefulness in these cases.
There is a wide variety of evidence to support benefits of low-fat diets versus low carbohydrate diets and vice versa. As of today, no one can tell us with certainty whether the well-worn dictum "calories in calories out" is really true. The National Weight Control Registry data give us some confidence in recommending that to lose weight most people need to alter their diet to reduce calories, and need to exercise on a near-daily basis.
Long-acting contraceptive devices should be the first choice of birth control for teenage girls, new recommendations from the American Academy of Pediatrics state. The guidelines were published online Sept. 29 in Pediatrics.
For critically ill cardiac surgery patients, fenoldopam does not reduce the need for renal replacement therapy, according to a study published online Sept. 29 in the Journal of the American Medical Association. The study was published to coincide with the annual meeting of the European Society of Intensive Care Medicine, held from Sept. 27 to Oct. 1 in Barcelona, Spain.
More Reading
Study results show many patients with chronic obstructive pulmonary disease (COPD) may experience cognitive deterioration that becomes more severe as their COPD worsens.