Relationship between Early Left Ventricular Myocardial Alterations and Reduced Coronary Flow Reserve

The Relationship between Early Left Ventricular Myocardial Alterations and Reduced Coronary Flow Reserve in Non-Insulin-Dependent Diabetic Patients with Microvascular Angina
Journal:International Journal of Cardiology (October 29, 2010)
Authors: D’Andrea A, Nistri S, Castaldo F, et al
Purpose:Researchers selected “a population of 45 normotensive patients with non-insulin dependent diabetes mellitus…with left ventricular ejection fraction > 50% and microvascular angina…[and] thirty-five age-and sex-matched healthy controls” to take part in a study that would help them “evaluate left ventricular systolic and diastolic myocardial function, and their relation to coronary flow reserve…”
Results:“All the patients underwent standard echocardiography, Tissue Doppler (TDI), two-dimensional strain (2DSE) imaging, and coronary flow reserve (CFR) measurement.” The authors found all tests to be “valuable non-invasive and easy-repeatable tools for detecting LV myocardial and coronary function in DM patients with microvascular angina.”
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