HCPLive

Air Pollution Linked to Atherosclerosis Marker

THURSDAY, April 25 (HealthDay News) -- Greater exposure to air pollution is associated with greater progression of carotid artery thickness, a marker of atherosclerosis, according to a study published online April 23 in PLOS Medicine.

Sara D. Adar, ScD, MHS, from the University of Michigan, in Ann Arbor, and colleagues examined the association between concentrations of fine particulate matter (PM2.5) and intima-medial thickness (IMT, as measured by ultrasound) of the common carotid artery in 5,362 individuals without pre-existing cardiovascular disease (45 to 84 years old) in six U.S. metropolitan areas.

The researchers found that carotid IMT increased by an average of 14 µm/y. After adjusting for factors such as smoking and age, higher average levels of residential PM2.5 were associated with increased IMT progression, but only among individuals in the same metropolitan area. Within the same metropolitan area, living at a residence with 2.5 µg/m³ higher levels of residential PM2.5 was associated with a 5.0 µm/y increased IMT progression annually compared with living in less polluted regions. Greater reductions in PM2.5 were associated with slower IMT progression.

"In a large prospective cohort study of adults without pre-existing cardiovascular disease, we found evidence that individuals with higher long-term residential concentrations of PM2.5 experience a faster rate of IMT progression as compared to other people within the same metropolitan area," Adar and colleagues conclude.

Full Text
Editorial

Copyright © 2013 HealthDay. All rights reserved.

Most Popular

Recommended Reading

Deaths and infections traced to duodenoscopes contaminated with carbapenem-resistant enterobacteriaceae infections are on the rise. The ECRI Institute, a nonprofit research and testing lab, today put out a "high priority hazard report" on procedures for cleaning the devices. It isn't easy.
When grass allergies are at their peak patients are usually at their lowest when forced to go outside. An early study looked at the role of immunotherapy in helping patients in the future.
Vocal chord cancer may not be one of the most well known forms of the disease but it is one of the more curable.
While most people thing they can just open their mouths and sounds and words come out, the process is actually considerably more involved.
$vAR$