HCPLive

Appropriate Use Criteria Established for Amyloid PET

 
TUESDAY, Jan. 29 (HealthDay News) -- Experts have agreed upon appropriate use criteria for positron emission tomography (PET) of brain amyloid β, according to a report published online Jan. 28 in Alzheimer's & Dementia.

Keith A. Johnson, M.D., from Massachusetts General Hospital in Boston, and colleagues, together with the Alzheimer's Association and the Society of Nuclear Medicine and Molecular Imaging, convened the Amyloid Imaging Task Force to provide guidance to dementia care practitioners, patients, and caregivers. Peer-reviewed, published literature was reviewed to develop a consensus opinion about the use of amyloid PET in specific clinical scenarios.

The researchers developed and agreed upon a series of specific appropriate use criteria to define the patients and clinical circumstances in which amyloid PET could be used. Amyloid imaging is appropriate when the following criteria are met: there is evidence of a cognitive complaint with objectively confirmed impairment; when Alzheimer's disease is a possible diagnosis, but that diagnosis is uncertain after a comprehensive evaluation by an expert; and when knowledge of amyloid pathology is likely to increase diagnostic certainty and alter management.

"Because both dementia care and amyloid PET technology are in active development, these appropriate use criteria will require periodic reassessment," the authors write. "Future research directions are also outlined, including diagnostic utility and patient-centered outcomes."

Multiple Task Force members and reviewers disclosed financial ties to pharmaceutical and other health care companies.
 

Abstract
Full Text (subscription or payment may be required)


Copyright © 2013 HealthDay. All rights reserved.
 

Most Popular

Recommended Reading

The US had been found to have a higher percentage of opioid use than in any other country.
While children with HIV may have low levels of a key immune cell, a new study shows that most will recover the cell with proper treatment.
Although the relationship between pain and spatial representation is unclear, a study published in Current Biology took steps in understanding how pain is activated in the brain and raised the possibility of reducing the sensation.
Patients administered minimally invasive surgery (MIS) colon resection procedures instead of open surgery leave the hospital quicker and require less follow up with physicians and fewer medical prescriptions.
$vAR$