HCPLive

Liver Transplant Outcomes No Worse With Echo Abnormalities

 
FRIDAY, Dec. 7 (HealthDay News) -- Intracardiac shunts (ICSs), diagnosed using an echocardiogram, or mild or moderate pulmonary hypertension (PH), do not affect short- or long-term mortality in liver transplant candidates, according to research published online in the Dec. 15 issue of The American Journal of Cardiology.

Matthew E. Harinstein, M.D., of the University of Pittsburgh Medical Center, and colleagues conducted a retrospective cohort study involving 502 consecutive patients (318 men) with end-stage liver disease who had echocardiography prior to liver transplantation. Contrast echocardiography was used to diagnose ICSs, and PH was defined as pulmonary artery systolic pressure >40 mm Hg.

The researchers found that more than 50 percent of the study population had at least two cardiovascular risk factors: ICSs were found in 16 percent, PH in 25 percent, and intrapulmonary shunts in 41 percent of liver transplant candidates. Short-(30-day) and long-term (mean, 41 months) mortality was not associated with ICSs or PH. Furthermore, no strokes occurred in those with ICSs.

"In conclusion, structural differences exist between various end-stage liver disease diagnoses. ICSs diagnosed by echocardiography are not associated with an increased risk of perioperative stroke or increased mortality. A diagnosis of mild or moderate PH on baseline echocardiogram is not associated with worse outcomes and requires further assessment," the authors write. "Based on these findings, patients should not be excluded from consideration for liver transplantation based solely on the presence of an ICS or PH."
 

Abstract
Full Text (subscription or payment may be required)

 
Copyright © 2012 HealthDay. All rights reserved.
 
 

Most Popular

Recommended Reading

To help hospitals implement antibiotics prescribing improvement programs, the CDC has developed several tools and guidelines and has begun partnering with states to implement stewardship programs, awareness campaigns, and stringent checklists.
Rheumatoid arthritis pain has been alleviated in half of patients enrolled in a study which used an electrical implanted device to emit magnetic pulses at the Academic Medical Center in Amsterdam, the Netherlands.
Topping this week’s list of must-see stories for physicians: A look at the real reason patients choose a doctor, plus what role should doctors play in curbing climate change and gun violence?
A recent study found that nearly half of patients given control over their electronic health records elected to withhold certain medical information from some or all of their healthcare providers. That impulse creates a number of challenges for physicians.
$vAR$