HCPLive Network

Internal Medicine World Report

Editor's Letter
Don't Count Us Out Just Yet
By Simon Douglas Murray, MD
The Ebola epidemic in Central Africa has riveted the American public. Press accounts of the homegrown case of a Liberian man who developed symptoms after arriving in Texas has driven anxiety higher. There is growing fear among many that the virus will spread rapidly in the US causing widespread death. This week a patient advised me to stock up on food and water and get a gun to prepare for the impending epidemic.
Cardiology
Discrepancy Among Device Therapy Requirement Evaluation Methods
By Rachel Lutz
Device therapy eligibility requirements are underestimated using 2D echocardiography compared to cardiac magnetic resonance imaging, according to a study from the Netherlands Heart Journal.
Hemoglobin A1c Levels Act as an Independent Gauge for Coronary Artery Disease
By Jacquelyn Gray
For individuals without diabetes, hemoglobin A1c (HbA1c) levels not only predicted the prevalence of coronary artery disease (CAD), but also anticipated its severity, according to research published in Mayo Clinic Proceedings.
Researchers Provide Recommendations for Proactive Statin Treatment of Hypercholesterolemia
By Jacquelyn Gray
For individuals with hypercholesterolemia, research published in the Journal of American Medical Association provided recommendations on statin use for treating their condition prior to age 80.
Pulmonology
Brief Report, Big Message: Profile of Pneumonia Pathogens Changed
By Jeannette Wick
A letter published online in the Journal of the American Medical Association presents the first microbiologic pathogens trend analysis in hospitalized patients in the United States.
Older Folks and Influenza: High Dose Vaccine 24% More Effective
By Jeannette Wick
Scientists from Sanofi Pasteur’s Swiftwater, PA facility have published results of a study indicating that a high-dose, trivalent, inactivated influenza vaccine (IIV3-HD or high dose Fluzone®) improves antibody responses to influenza among adults 65 years of age or older.
In-hospital Pharmacologic Prophylaxis not Linked to Decrease in Venous Thromboembolism Prophylaxis
By Jacquelyn Gray
A study published in the Journal of the American Medical Association found hospitals’ administration of pharmacologic venous thromboembolism (VTE) prophylaxis was not associated with lower rates of VTE.
Gastroenterology
Managing Diverticulitis Without Surgery
By Gale Scott
In an article in Annals of Surgery, Debbi Li, MD and colleagues at the University of Toronto, Toronto, Ontario, Canada report on a retrospective study of 14,124 diverticulitis patients cared for without surgery. The research goal was to quantify the risks of readmission and emergency surgery when patients did not get a prophylactic colectomy.
Treatment Guidelines Cut Clostridium Difficile Mortality
By Gale Scott
Clostridium difficile (C. diff) infection is now the leading cause of infectious nosocomial diarrhea in the industrialized world. But by following Infectious Disease Society of America (IDSA) treatment guidelines, clinicians can significantly reduce recurrence and mortality, a Texas Tech University Health Sciences Center School of Pharmacy team reports.
US Residents of Indian Origin Have Elevated Risk of Inflammatory Bowel Disease
By Jackie Syrop
Patients of Indian ancestry living in the United States are at greater risk for all types of inflammatory bowel disease (IBD) than other American populations, according to a new study by Reenu Malhotra, MD, and colleagues published online in Clinical Gastroenterology and Hepatology on July 29, 2014.
Rheumatology
Increased Development in Carpal Tunnel Syndrome
By Adam Hochron
As people spend more time sitting and working in front of computer screens, studies have shown the risk of developing carpal tunnel syndrome (CTS) has grown. A team of researchers recently worked to take a deeper look at specific factors and their roles in the development in the condition.
Option of Arthroscopic Surgery for Degenerative Meniscal Tears
By Adam Hochron
A recent study published in the Canadian Medical Association Journal looked at the steady progression of treatments for patients with degenerative muscular tears as well as the different efficiency levels between those patients who had surgery and those who took another treatment option.
Jaw Osteonecrosis as Potential Adverse Effect to Oral Bisphosphonate Therapy
By Adam Hochron
In a review published in the New England Journal of Medicine, Brett noted that the results from the first study suggested that in Taiwan, one out of every 200 patients who are “long-term users of oral alendronate,” develop the condition.
Psychiatry
Addressing Behavior Concerns in Adolescents with Omega-3 Supplements
By Rachel Lutz
Omega-3 supplementation can help reduce behavioral issues in adolescents who may be particularly prone to oxytocin receptor gene methylation.
Withdrawal Symptoms Cease over 12 Months When Cannabis Users Acknowledge Use
By Rachel Lutz
Cannabis users who acknowledge their problem and report withdrawal symptoms are likely to increase abstinence over a 12-month period, according to research published in the Journal of Addiction Medicine.
Mental Health Drugs: High Risk for Adverse Events
By Jeannette Wick
Prescription medications for mental health diagnoses (e.g. antidepressants, antipsychotics, and mood stabilizers) consume approximately 25% of commercial health insurers’ pharmacy budgets and almost 35% of public payers’ pharmacy spending. In 2011, an estimated 26.8 million US adults—more than 11%—took prescription medications for mental illness.
Neurology
Potential Drug LY2951742 to Prevent Migraines?
By Gale Scott
Physicians have few effective weapons to treat a migraine, an ailment that accounts for more than half of disability with a neurological cause. Chronic migraine is said to affect 2% of the world’s population.
Hyperalgesia May Be Reversible After Spinal Pain Pathway Reactivation
By Jackie Syrop
Research using an animal model of pain suggests that mechanical hyperalgesia may be reversible in mice after spinal pain pathways are reactivated in a manner analogous to memory reconsolidation.
Oral Fluoroquinolone Use and Risk of Peripheral Neuropathy
By Jackie Syrop
Current users of oral fluoroquinolone (FQs) antibiotics, especially new users of FQs, are at higher risk of developing peripheral neuropathy (PN), concludes a recent study published in Neurology.