Researchers reported that treatment with isotretinoin is not only associated with significant clinical improvement in patients with moderate to severe acne, but it also did not cause worsening of depression or suicidal thoughts in any of the patients in the study.
The use of filtered sunlight is both safe and noninferior to conventional phototherapy for the treatment of neonatal hyperbilirubinemia. This is important because severe neonatal hyperbilirubinemia can lead to fatal complications, and because in some cases, existing guidelines for managing neonatal hyperbilirubinemia explicitly discourage the use of sunlight for the treatment.
A recently published article in JAMA Dermatology explored the curious relationship between psoriasis and depression, since psoriasis has been considered a risk factor for depression, and depression a trigger for psoriasis.
Pachyonychia congenita (PC), a rare skin disorder, can cause an inordinate amount of neuropathic pain, a study in Clinical and Experimental Dermatology confirms. In the chilling words used by the researchers, “The health states observed in this sample are at a level that the average US citizen would forfeit one-third of their remaining lifespan to avoid.”