General Medicine

Although low-dose computed tomography (LDCT) screening may be beneficial for some individuals, there are concerns about the potential harms of screening.

For patients admitted to the intensive care unit (ICU), nighttime intensivist staffing is associated with reduced in-hospital mortality in ICUs that have low-intensity daytime staffing.

The majority of patients with long-bone fractures receive inadequate pain medication in the emergency department, and disparities in management exist.

The first generic versions of Plavix (clopidogrel bisulfate) have been approved by the U.S. Food and Drug Administration.

For men with localized high-risk prostate cancer, neoadjuvant androgen deprivation therapy with abiraterone acetate (AA) plus leuprolide acetate (LHRHa) is well tolerated and has good pathological complete/near complete response (pCR/near pCR) rates.

For contact sport athletes, repetitive head impact during a single season is associated with poorer measures of new learning and poorer performance on cognitive measures

Although the majority of patients admitted to the intensive care unit (ICU) with status asthmaticus (SA) require mechanical ventilation, the rates of mortality and complications are very low.

High-volume endovascular stroke centers provide faster times to treatment, and patients are more likely to have good clinical outcomes and successful reperfusion.

Poor executive performance, as measured with the Trail Making Test (TMT)-A and -B, can identify elderly men who are at higher risk of death after a first-ever stroke.

Variation in regional hospital readmission rates for congestive heart failure is due more to the availability of care and socioeconomic factors than hospital performance or patients' degree of illness.

Average emergency department wait times for adult patients with psychiatric emergencies is 11.5 hours, and can be even longer for those who are older, uninsured, or intoxicated.

Middle-aged fitness is significantly associated with lower health care charges in older age. Findings persist even after adjusting for other risk factors in both men and women

For children in the emergency department, non-private insurance status is associated with decreased diagnostic testing and interventions.

Globally, nearly two million new cancer cases are caused by infectious agents each year.

Pediatric content in the labeling of drugs has improved from 1975 to 1999, but still only 46 percent of drug labeling in the electronic Physicians' Desk Reference (ePDR) includes pediatric information.

Sperm cells travel in the intersection of channel walls, not in central channels, and experience frequent collisions.

For heart failure patients with reduced left ventricular ejection fraction (LVEF) who are in sinus rhythm, there is no significant overall difference in the primary outcome between treatment with warfarin and treatment with aspirin.

Clinical studies registered with ClinicalTrials.gov from 2007 and 2010 are predominately small, single-center trials and contain significant heterogeneity in methodology.

Using a weighted risk index, the highest-risk outpatient surgery patients have an almost 20-fold increase in risk of venous thromboembolism (VTE) requiring therapy.

Electronic information systems can be used to generate detailed information about blood component use by individual providers and surgical services, and they reveal significant variation in utilization.