Hospital Medicine

Following reports of invasive meningococcal disease (IMD) among men who have sex with men (MSM), the New York City (NYC) Department of Health and Mental Hygiene (DOHMH) has recommended that MSM who have engaged in intimate contact with another man should undergo vaccination.

For patients with rheumatoid arthritis (RA), the median time to discontinuation of therapy is 25.1 months, with longer time to discontinuation noted for those receiving tumor necrosis factor inhibitors (TNFi's).

In older adults, concomitant administration of clarithromycin, or erythromycin, with a statin that is metabolized by cytochrome P450 isoenzyme 3A4 (CYP3A4) increases the risk for statin toxicity.

Initial data show similar efficacy but different costs among injectable insulin treatments for patients who fail oral antidiabetic drugs.

A recent study suggests that skipping breakfast in overweight women may lead to insulin resistance.

The efficacy of new medical treatments compared with placebo has sharply declined over the last few decades, suggesting that comparative effectiveness studies are needed.

Duloxetine is a moderately cost-effective treatment for chronic low back pain (CLBP) compared with other post-first-line oral medications.

About three-quarters of physicians report in a survey that their practice either has a fully implemented electronic health record (EHR), uses a hospital or corporate EHR, or is in the process of implementing an EHR.

For adults, individual daytime noise exposure correlates with changes in heart rate variability, with effects less pronounced for noises of 65 dB(A) or more.

For injecting drug users, daily oral use of an antiretroviral, tenofovir disoproxil fumarate (tenofovir), can reduce the risk of HIV transmission.