Neurology

Statin use during hospitalization for ischemic stroke significantly improves the likelihood of being discharged to home or institution.

Based on diffusion tensor imaging (DTI), the microstructural changes seen in the genu and body of the corpus callosum in recently detoxified alcohol-dependent patients are found to improve after one year of abstinence.

Impact of exercise on pain perception suggests potential of physical activity in pain management. Athletes seem to have significantly higher pain tolerance than normally-active people.

For siblings of children with autism, a gender-specific genetic score based on single nucleotide polymorphisms (SNPs) in genes with biological and functional relevance to autism can predict the risk of developing an autism spectrum disorder (ASD).

For pediatric patients with tumors that have genetic aberrations in the anaplastic lymphoma kinase (ALK) gene, crizotinib is well tolerated and has antitumor activity.

The first generic versions of Plavix (clopidogrel bisulfate) have been approved by the U.S. Food and Drug Administration.

Oxytocin administered via nasal spray to children and adolescents with autism spectrum disorders (ASDs) seems to increase activity in brain regions known to process social information, as seen on functional magnetic resonance imaging (fMRI).

In order to facilitate shared decision making in autism spectrum disorder (ASD) treatment, primary care pediatricians (PCPs) need more training, and parents need to be guided in terms of realistic expectations regarding the role of the PCP.

Percutaneous endoscopic gastrostomy (PEG) feeding tubes significantly increase the risk of new pressure ulcers and do not promote the healing of existing pressure ulcers in nursing home residents with advanced cognitive impairment.

Variants of the alpha-synuclein gene (SNCA) are associated with a higher risk of a more rapid decline in motor function in patients with Parkinson's disease.

Multiple sclerosis patients taking natalizumab are at higher risk of developing progressive multifocal leukoencephalopathy (PML) if they are positive for the anti-JC virus antibodies, have been treated with immunosuppressants, and have been treated with natalizumab for longer periods.

For contact sport athletes, repetitive head impact during a single season is associated with poorer measures of new learning and poorer performance on cognitive measures

High-volume endovascular stroke centers provide faster times to treatment, and patients are more likely to have good clinical outcomes and successful reperfusion.

Poor executive performance, as measured with the Trail Making Test (TMT)-A and -B, can identify elderly men who are at higher risk of death after a first-ever stroke.

The lifetime prevalence of nocturnal wandering with abnormal state of consciousness (NW) is approximately 30 percent in the U.S. general population.

Based on the report of a patient who died after taking one dose of the multiple sclerosis (MS) drug Gilenya (fingolimod) and on clinical trial data, the U.S. Food and Drug Administration is recommending extended monitoring for certain patients taking this drug.

Treatment with sumatriptan and naproxen sodium (suma/nap) is well tolerated and effective in reducing migraine pain in adolescents.

Smoking cannabis is associated with a reduction in spasticity for patients with multiple sclerosis (MS).

Youth with autism spectrum disorders (ASDs) are at high risk for not participating in postsecondary education or employment, particularly in the first two years after high school.

Treating acute ischemic stroke patients who are warfarin users with tissue plasminogen activator (tPA) does not increase the risk of intracranial hemorrhage (ICH).