It is unclear how many people have pituitary incidentaloma, but imaging and autopsy studies indicate they are quite common and occur in up to one-third of patients. Fortunately, the vast majority of these serendipitously discovered tumors are clinically insignificant. A management guideline in the Annals of Endocrinology brings endocrinologists up to date on current thinking about pituitary incidentaloma management.
Some studies have shown the benefit of a blunt, Whitacre-type needle in reducing the incidence of intravascular injection during TFESI, but other studies showed that a short-bevel needle did not reduce the incidence of intravascular injection in lumbar TFESI compared to long-bevel, Quincke-type needles.
There has been a great deal of study on the placebo effect in the medical literature, and despite some evidence suggesting that placebo response rates in randomized controlled trials are higher in children and adolescents compared to adults, there has only been limited research involving the placebo response of children.
Obsessive–compulsive disorder (OCD) presents several diagnostic and treatment challenges, in part because etiology and pathogenesis remains relatively unknown. Most studies of OCD focus on adult patients, but there have been some studies of OCD onset before the age of 6 years, and the vast majority of OCD patients (80%) report that related symptoms began before age 18.
A recent study in The Journal of Headache and Pain sheds some additional light on the chronobiological experience of patients with cluster headache (CH). However, it still leaves lingering mysteries around the pattern of pain CH that patients typically experience, the triggers of those headaches, and the mechanisms and interactions that drive headache frequency and severity.