Primary Care

For patients presenting with dyspnea, the additional measurement of B-type natriuretic peptide (BNP) levels increases the certainty of diagnosis of heart failure and accelerates initiation of appropriate treatment.

For children in the emergency department, non-private insurance status is associated with decreased diagnostic testing and interventions.

Dr. John R. Rinker, II Assistant Professor of Neurology Outlines some highlights of his study The Nature of MS: Epidemiology, Diagnosis, Natural History and Clinical Course.

Pediatric content in the labeling of drugs has improved from 1975 to 1999, but still only 46 percent of drug labeling in the electronic Physicians' Desk Reference (ePDR) includes pediatric information.

For survivors of acute myocardial infarction (AMI), residential proximity to a major roadway at the time of AMI is linked to an increased risk of 10-year mortality.

A new meningococcus serogroup B vaccine is strongly immunogenic against multiple strains and well tolerated in healthy adolescents.

Middle school entry vaccination requirements may increase coverage for adolescent vaccines, but education-only requirements do not appear to have an impact.

About half of young adolescents who have self-harmed were frequently bullied, and self-harm among the bullied is more likely in those with mental health problems, a family history of suicide, or a history of being physically abused by an adult.

In the first long-term active-comparator trial of efficacy and augmentation in restless leg syndrome (RLS), outcomes with pregabalin were better than those observed with pramipexole.

Although the intra-cerebral hemorrhage (ICH) score at hospital admission is typically used to estimate the potential prognosis in stroke patients, a new study suggests that the 24-hour ICH score is a more accurate assessment.

According to a randomized, controlled clinical trial reported at the Emerging Science session, pregabalin was found effective in relieving chronic neuropathic pain and pain-related sleep disturbances associated with spinal cord injury.

Results from the FREEDOMS II trial found oral fingolimod administered at a daily dose of 0.5 mg to reduce relapse rates by almost 50% in patients with relapsing-remitting multiple sclerosis (RRMS).

Mark F. Mehler, MD, discussed how brain and behavior are becoming better understood through the emerging discipline of epigenetics.

The 2012 Annual Meeting of the American Academy of Neurology presented a phase 3 randomized, double-blind clinical trial which found that levodopa-carbidopa intestinal gel was more effective than standard oral levodopa-carbidopa.

A text messaging-based intervention increases influenza vaccination compared with usual care in a low-income, urban population, although overall rates of vaccination remain low.

An investigational oral drug for multiple sclerosis (MS), called ONO-4641, reduced the number of lesions detected on magnetic resonance imaging (MRI) scans

Updated guidelines for prevention of chronic migraine headache were unveiled during the 2012 Annual Meeting of the American Academy of Neurology.

A new study presented at the 2012 Annual Meeting of the American Academy of Neurology suggests that the drug florbetaben can be used as a biomarker with positron emission tomography (PET) imaging to diagnose AD by detecting amyloid plaques in the brains of living people suspected of having AD.

The prevalence of obesity among children younger than 6 years in a Massachusetts cohort was stable from 1999 to 2003, and decreased from 2004 to 2008.

The zoster vaccine is safe and well tolerated in older adults, despite an increased risk of allergic reaction in the days following vaccination.