In this MEDcast episode, Diana Isaacs, PharmD, BC-ADM, CDCES, and Natalie Bellini, DNP, FNP-BC, interview Dr Juan Frias to explore the mechanism of GLP-1 and GIP agonists in diabetes and weight management and examine key findings from clinical trials for the latest GLP-1/GIP dual agonist.
1:00 Effect of incretins on blood glucose and body weight
3:24 Evolution of GLP-1 agonists
7:45 Mechanism of tirzepatide- dual GLP-1/GIP agonist
10:35 Overview of SURPASS and SURMOUNT trials for tirzepatide
17:45 Benefits vs. risks of GLP-1 agonists
21:45 Sustainability of weight loss with incretin-based therapies
25:30 Future of metabolic diseases management