CME Instructions

Cardiology Review® Online, August 2014, Volume 30, Issue 4

CME Reviews: Volume 30, No. 4

Release date: August 15, 2014

Expiration date: August 15, 2015

Media used: Internet-based

Estimated time to complete this CME activity: 1 hour

Statement of Need

Cardiovascular disease (CVD) is the leading cause of death in the United States. It is estimated that 83 million American adults have 1 or more forms of CVD. New agents, procedures, and interventions have improved patient outcomes, decreasing mortality and morbidity rates. However, as the population ages and as younger adults develop comorbidities due to unhealthy lifestyles, the patient population at risk for cardiovascular events is increasing.

Care for patients with CVD has become increasingly complex, and community-based cardiologists often struggle to stay up-to-date with the volume of new data. The overall goal of this publication is to provide timely and pertinent original research articles that review current guidelines, practices, and new developments in the field of cardiovascular medicine. The publication also emphasizes preventing CVD by modifying risk factors through such strategies as healthy eating, regular exercise, and avoidance of smoking.

Target Audience

The target audience for this activity is cardiologists.

CME Learning Objectives

At the conclusion of this activity, participants should be able to:

1. Analyze the findings of the study by Meier et al on the impact of coronary collateral circulation on outcomes in patients with NSTE-ACS and how the data apply to antithrombotic regimens for individual patients.

2. Compare and contrast the effects of a website-based lifestyle and medication intervention group with a live counseling lifestyle and medication intervention group with respect to reducing 10-year Framingham Risk Scores at 4 months and 12 months as described by Keyserling et al.

3. Describe what the DES LATE study concludes about the optimal duration of dual antiplatelet therapy with aspirin and clopidogrel after drug-eluting stent implantation.

4. Explain which patients would be the most appropriate candidates for a Leadless Cardiac Pacemaker based on the findings of Reddy et al.

5. Assess the evidence on supplements and alternative medications for primary prevention of cardiovascular disease as described by the study by Moyer et al.

6. Describe the findings of Gregg et al findings on the rates and trends of diabetes-related complications in the US population between 1990 and 2010.

Financial Disclosure

As a sponsor accredited by the ACCME, it is the policy of Physicians’ Education Resource®, LLC (PER®), to require the disclosure of anyone who is in a position to control the content of an educational activity. All relevant financial relationships with any commercial interests and/or manufacturers must be disclosed to participants prior to the beginning of each CME activity. PER® has identified and resolved all conflicts of interest prior to the release of this activity.

The following individuals have relevant financial relationship(s) with commercial interests to disclose:

Authors: Alison L. Bailey, MD—Grant/ Research Support: Astra Zeneca; Dimitri P. Mikhailidis, BSc, Sc, MD, FRSPH, FCP, FFPM, FRCP, FRCPath—Speaker’s Bureau: Merck Sharpe and Dohme

The following individuals have no relevant financial relationships with commercial interests to disclose:

Authors: Saurav Chatterjee, MD; Niki Katsiki, MsC, PhD, MD, FRsPh; Richard A. Lange, MD, MBA; Glenn N. Levine, MD, FACC, FAHA; Kalyanam Shivkumar, MD, PhD; Steven M. Stevens, MD; Thomas F. Whayne, Jr, MD, PhD, FACC

Planner, reviewer, and editor-in-chief: Debabrata Mukherjee, MD, MS, FACC

PER® planners and staff: Megan O’Connell; Jackie Syrop; Emily Valko

Cardiology Review staff: Bea Riemschneider

Off-Label Disclosure and Disclaimer

This CME activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient’s medical condition.

Sources of Funding

No educational grants from commercial interests were received.

Instructions for Receiving Credit

In order to receive a CME certificate for this activity, participants must

· Read each review.

· Take the posttest and record their answers online at A passing score of 70% or higher is required to obtain a CME certificate.

· Complete the CME activity evaluation at Participants can immediately download their CME certificates upon successful passing of the posttest and completion of the CME activity evaluation.

Accreditation and Designation of Credit

Physicians’ Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Physicians’ Education Resource®, LLC, designates this enduring material for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.



Debabrata Mukherjee, MD, MS, FACC

Chairman, Department of Internal Medicine

Chief, Cardiovascular Medicine

Professor of Internal Medicine

Texas Tech University Health Sciences Center

El Paso, TX

Alison L. Bailey, MD

Assistant Professor of Medicine

Director, Cardiac Rehabilitation

Associate Director, Cardiovascular Fellowship Program

Gill Heart Institute

University of Kentucky

Lexington, KY

Saurav Chatterjee, MD

Fellow, Cardiovascular Diseases

Division of Cardiology

St. Luke’s-Roosevelt Hospital Center

New York, NY

Niki Katsiki, MsC, PhD, MD, FRsPh,

Aristotle University of Thessaloniki

Thessaloniki, Greece

Richard A. Lange, MD, MBA

Founding President and Dean

Texas Tech University Health Sciences Center El Paso

El Paso, TX

Glenn N. Levine, MD, FACC, FAHA

Professor of Medicine

Baylor College of Medicine

Director, Cardiac Care Unit

Michael E. DeBakey Medical Center

Houston, TX

Dimitri P. Mikhailidis, BSc, Sc, MD, FRSPH,


Academic Head, Department of Clinical Biochemistry

(Vascular Disease Prevention Clinics)

Royal Free Hospital Campus

University College London Medical School

London, England

Kalyanam Shivkumar, MD, PhD

Professor of Medicine & Radiology

Director, UCLA Cardiac Arrhythmia Center, & EP Programs

UCLA Health System

David Geffen School of Medicine at UCLA

Los Angeles, CA

Steven M. Stevens, MD

UCLA Cardiac Arrhythmia Center

Ronald Reagan UCLA Health System

David Geffen School of Medicine at UCLA

Los Angeles, CA

Thomas F. Whayne, Jr, MD, PhD, FACC

Professor of Internal Medicine

Division of Cardiovascular Medicine

Gill Heart Institute

University of Kentucky

Lexington, KY

Provider Contact Information:

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