CME TEST

Cardiology Review® Online, April 2012, Volume 28, Issue 2

PCI for STEMI and NSTEMI Review

1. A recent meta-analysis by Singh et al found which of the

following?

a. In-hospital mortality was higher in patients with percutaneous

coronary interventions (PCIs) at centers without

on-site surgery

b. PCIs performed at centers without on-site surgery were not

associated with a higher incidence of in-hospital mortality

c. PCIs performed at centers without on-site surgery were associated

with a higher incidence of emergency bypass surgery

d. The mortality rate for nonprimary PCI was lower at centers

without on-site surgery

2. Which of the following suggests the possibility of selection

bias in the meta-analysis by Singh et al?

a. The authors followed the MOOSE guidelines for inclusion

b. The first author was not associated with previous studies

included in the analysis

c. One author extracted the data

d. All of the above

e. None of the above

Pharmacoepidemiology: Adverse Events Review

3. The study conducted by Habel et al found the use of medication

for attention-deficit/hyperactivity disorder was associated

with:

a. Increased risk of myocardial infarction

b. Increased risk of sudden cardiac death

c. Increased risk of stroke

d. All of the above

e. None of the above

4. Which of the following was NOT a limitation in the Habel

study?

a. Sensitivity analysis was used to control confounding variables

b. The study excluded adults older than 65 years

c. Medication use was based on electronic records of prescriptions

dispensed

d. ICD-9/ICD-10 code—based definitions were used for suspected

cases

Heart Failure Review

5. A study by Flammer et al found which of the following

cardiovascular effects of chocolate?

a. Cocoa-liquor—free chocolate significantly improved endothelial

function

b. Flavanol-rich chocolate significantly improved endothelial

function

c. Flavanol-rich chocolate significantly reduced insulin sensitivity

d. Cocoa-liquor—free and flavanol-rich chocolate significantly

reduced oxidative stress

Antiplatelet Medications Review

6. A meta-analysis of antiplatelet function found all of the

following EXCEPT:

a. CYP2C19 genotype was strongly associated with cardiovascular

events

b. CYP2C19 genotype was associated with less platelet inhibition

c. CYP2C19 genotype was associated with lower levels of active

clopidogrel metabolites

d. All of the above

e. None of the above

Hypertension Review

7. According to the analysis by Kostis et al, long-term treatment

with chlorthalidone showed a gain in life expectancy of:

a. 1 month per year of therapy

b. 1 day per month of therapy

c. 2 days per year of therapy

d. A gain in life expectancy was not observed in patients treated with chlorthalidone

Women’s Cardiovascular Health Review

8. A study by Mora et al found all of the following EXCEPT:

a. A significant association of high HDL-C with a decreased

risk of coronary artery disease (CAD)

b. An association of apo A-1 with a decreased risk of CAD

c. A significant association of apo B100 with a decreased risk

of CAD

d. A significant association of high HDL-C with a decreased

risk of stroke

Imaging Review

9. According to the retrospective study by Bischoff et al, what

percentage of patients were appropriately stratified by calculation

of coronary artery calcification (CAC) using coronary

computed tomography angiography (CCTA)?

a. 25%

b. 50%

c. 75%

d. 90%

Diabetes and Chronic Kidney Disease (CKD) Review

10. Results from Shurraw et al showed which of the following

after examining the effects of glycemic control in patients with

diabetes and CKD?

a. Patients with CKD stage 3 or 4 and a HbA1c >9% had a

lower risk of death compared with patients with HbA1c < 7%

b. Patients with CKD stage 4 and a HbA1c >9% had a significantly

higher risk of stroke compared with patients with

HbA1c <7%

c. Intensive glycemic control (target HbA1c <6.5%) for patients

with either HbA1c >8% or HbA1c <6.5% showed a

higher risk of mortality

d. All of the above

e. None of the above