Eli Lilly & Co. is taking a shot at Sanofi with a new drug that matches Sanofi's Lantus at controlling blood sugar, but also helps patients lose weight.
Eli Lilly & Co. is taking a shot at Sanofi with a new drug that could be better than Sanofi’s Lantus. While the two drugs were matched at controlling blood sugar, Lilly’s also helped patients with Type 2 diabetes lose weight.
Developed with Boehringer Ingelheim, LY2605541, is just one of at least four regulatory submissions within the next two years. On Monday, Lilly announced the results of the trial that showed weight lose for type 2 diabetes patients.
Over the course of 12 weeks, patients who took Lilly’s experimental insulin lost an average of 1.28 pounds compared to a weight gain of 0.68 pounds with Lantus. While the weight loss is modest, is could be a commercial advantage for Lilly.
Lilly’s insulin also worked better after eight weeks in patients with type 1 diabetes.
The company’s stock ended the day up 0.36% on Tuesday. Right now it is at the higher end of its 52-week range: $33.75 to $42.03.
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Another drug in the pipeline for Lilly in the diabetes market right now is empagliflozin in Phase III testing. A trial for the drug will complete this year with possible submission in the U.S. and Europe in 2013. Either alone or as an add on to metformin, empagliflozin reduced A1C, fasting plasma glucose and body weight in adults with type 2 diabetes.
Although Lilly has not had a presence in basal analogs, the company is currently working on two in late-stage development. Both are developed with Boehringer and if the trials prove successful, the company expects to submit the products to regulatory authorities in 2013.
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