Jenna Honeycutt from the University of North Carolina: Study Contradicts Prior Views of Macrophages in HIV

Strategic Alliance Partnership | <b>UNC Institute for Global Health & Infectious Diseases</b>

In previous studies it had been shown that macrophages were not targeted by HIV when looking at how the virus develops. New research of mouse models has shown evidence that that may not be the case.

Previous studies have shown that as the human immunodeficiency virus (HIV) develops, the virus does not target macrophages. However, new research conducted in mouse models show evidence that indicate that may not be the case.

Jenna Bone Honeycutt, PhD, from the University of North Carolina (UNC) discussed the new HIV research with MD Magazine. Honeycutt and colleagues looked at the virus in relation with macrophages and found results that contradict previous beliefs. It was thought that macrophages become infected by absorbing T-cells in the body, but the UNC research involved animal models that were devoid of T-cells.