Psychiatry

Investigators found girls with depression and anxiety responded especially well to melatonin treatment, suggesting the potential of sleep interventions in reducing the risk of self-harm.

There was also significantly greater reductions in anxiety, Afghan-cultural distress symptoms, and psychiatric difficulties compared to the treatment as usual group.

The probability of using a firearm when alcohol is consumed was higher in the male decedents compared to female decedents.

Future research could explore the factors contributing to this disparity and identify effective interventions to reduce tobacco use in this population.

Patients in the top half of the cohort for both clinical severity and instability were at an increased risk of hospitalization than those at the bottom half of both dimensions

Various psychiatric symptoms, including more severe negative symptoms, lower cognition status, and lower excited symptoms were significantly linked to drug-induced parkinsonism induction.

TCAs caused more examples of severe dry mouth, both objectively and subjectively, while SSRIs were associated with less severe symptoms.

There was very little evidence of an effect growth or increased risk of psychiatric or neurological adverse events in the methylphenidate group compared with the no-methylphenidate group.

Prism for PTSD uses self-neuromodulation techniques to lower the amygdala-derived-EPP biomarker, which is linked to the amygdala and emotion regulation system.

There was a lower probability of initiating psycholeptics and having postpartum psychiatric emergencies in the early discontinuer and late discontinuer groups compared to the continuers.

Zuranolone is being evaluated as a 14 day, rapid-acting, once-daily, oral treatment for adult patients with MDD and PPD. The drug is an oral neuroactive steroid GABA-A receptor positive allosteric modulator.

New cohort analysis data show women with fibromyalgia are at an increased risk of depression—which is also correlated with a worse life expectancy over 8 years.

The results show 28.9% of the aripiprazole augmentation group achieved remission, compared to 28.2% of the bupropion augmentation group and 19.3% of the bupropion switch group.

The results from a Bayesian reinforcement learning model showed the antidepressant placebo trial-wise expectancies were updated by composite learning signals multiplexing sensory evidence and trial-wise mood.

The US disproportionately arrests individuals with mental illness, and relies on police officers to respond to health crises. Practical, preventive clinical measures need to help stop the cycle.

Exposure to maternal, paternal, or full sibling major depression was associated with a two-fold higher risk of major depression for men.

Patients with with depression and AHI ≥ 30 show the greatest risk of all-cause mortality.

The connection between different ADHD subtypes and mood disorders has not been fully explored.

Singh presented during the recent APSARD conference. onthe topic of ADHD and bipolar disorder.

An international review of data show certain antidepressants may benefit conditions like fibromyalgia, but many trials are actually inconclusive.

The same risk was not found for offspring of fathers with primary immunodeficiencies.

Crosbie presented results from a small pilot study testing a video game platform for patients with executive function deficits during the annual APSARD meeting.

Based on data from the systematic review, investigators urge for the prioritization of sleep as a core clinical target and further investigation across the stages of psychosis.

Those who were assigned female at birth, had worse physical health, and self-reported symptoms of anxiety, were vulnerable to poor sleep quality in all aspects.

In what investigators are calling the largest study of its kind ever conducted in the US, results of the 2-year study, which included more than 300 transgender or nonbinary youth, underline the positive benefits seen with receipt of gender-affirming hormone therapy among this patient population.

Personality disorders, adjustment disorder, bipolar disorder, insomnia, and anxiety disorders were risk factors associated with postpartum depression.

Sleep and epilepsy have been described as "unfortunate bedfellows" due to the complex relationship, and yet caretakers report a lack of support managing these issues commonly experienced by children.

Based on the identified biomarkers, it was possible to distinguish patients with a good predictive value for pain, sleep, and anxiety.

The potential mediating role of inflammation at 9 years, measured by CRP and IL-6, was investigated in the relationship between sleep and ADHD.

Participants in the iPCIT group had significantly lower levels of externalizing problems and higher levels of compliance to caregiver direction compared to the referrals as usual group.