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FDA Warning: Disabling Joint Pain Seen in Diabetes Drugs
The US Food and Drug administration today issued a warning that the type 2 diabetes medicines sitagliptin (Januvia/Merck) linagliptin (Tradjenta/BI), and alogliptin (Nesina/Takeda) “may cause joint pain that can be severe and disabling.”
Ebola can persist in wastewater, plastic, and steel and the virus has even gone undetected in a blood test. But how many physicians are actually prepared to properly assess a patient with a potential case of the deadly disease? A team from the Massachusetts General Hospital (MGH) found that physicians least likely to encounter patients with Ebola were more likely to use excessive approaches.
Fred Lublin, MD, discusses the molecular, immunologic, other treatments strategies being assessed for progressive multiple sclerosis.
A long-term study of alemtuzumab for treatment of Behçet disease (BD) yields promising evidence that the monoclonal antibody can successfully treat refractory and relapsing courses of the disease.
Patricia K. Coyle, MD, and Fred Lublin, MD, describe the risk factors for developing progressive multifocal leukoencephalopathy (PML) in patients with MS.
Stress resulting from frequent migraine headaches may contribute to the development of medical and psychological comorbidities that can result in an ugly cycle of more migraines, according to a study in the Journal of Pain Research.
Two comprehensive reviews in the Indian Journal of Psychiatry looked at the use of pharmacologic therapy for psychiatric conditions during pregnancy and lactation. One review looked at mood stabilizers and the other focused on antidepressants, anxiolytics, and hypnotics.
A Japanese study suggests that parental bonding style during childhood is associated with the prevalence of chronic pain in adults in the general population and that the association is more robust for paternal bonding than for maternal bonding.
Three recent studies – in three very different publications – add to a growing cache of evidence showing that music can have significant benefits for patients with pain.

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