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Mepolizumab Reduces Type 2 COPD Exacerbations Across Variable BEC Levels
Rare Disease Day 2026: Kidney Diseases Enter Optimistic Therapeutic Era
GLP-1s Linked to Reduced Asthma Exacerbations, With Ruchi Patel, MD
Vaginal Seeding Partially Modifies Infant Microbiome in ACTIVATE, With Jose Clemente, PhD
FDA Grants Accelerated Approval to Navepegritide for Achondroplasia in Children Aged 2 Years and Older
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Diabetes Dialogue: Orforglipron, Retatrutide, and Other GLP-1 Updates
Isaacs and Bellini discuss recent updates on Eli Lilly's orforglipron and retatrutide and Novo Nordisk's UBT251, along with other recent GLP-1 news.

Diabetes Dialogue: Launch of the Zepbound KwikPen
Cohosts Diana Isaacs, PharmD, and Natalie Bellini, DNP, discuss the recent release of Eli Lilly's Zepbound as an injectable with the KwikPen.

Diabetes Dialogue: Implantable Insulin Pumps and Interoperability
Diana Isaacs, PharmD, and Natalie Bellini, DNP, discuss the Portal implanted insulin pump, which has received Breakthrough Device designation from the FDA.

Diabetes Dialogue: Oral Ozempic and the Risks of Compounding Formulas
Diana Isaacs, PharmD, and Natalie Bellini, DNP, discuss Ozempic’s approval in a higher-dose oral form and lingering concerns over compounded drugs.

When Platelet Increments Matter, With Ruchika Goel, MD
Low post-transfusion platelet increments did not predict mortality or length of stay in pediatric patients.

Liver Lineup: Nutrition, Alcohol, and Liver Health in the New Dietary Guidelines
Reau and Brown are joined by Amanda Van Jacobs, MS, RDN, and Jessica Mellinger, MD, to discuss the new dietary guidelines through the lens of liver health.

Obesity’s Double Role in CKD as Comorbidity and Driver
Obesity is common in CKD and drives hyperfiltration, nephron stress, and progressive kidney injury, according to experts, Kramer and Perkovic, and trial data.

Liver Lineup: Managing MASLD and MASH Amid Limited Awareness, Overlapping Risk Factors
Reau and Brown discuss new data on MASH/MASLD, including awareness, referral patterns, discussions around alcohol, and emerging pharmacotherapies.

Liver Lineup: Advances, Gaps, and What’s Next in Viral Hepatitis
Reau and Brown discuss recent research in hepatitis B, C, and D, including use of statins, GLP-1s, and more.

Implementing Age-Specific Care For Young Adults With Glomerular Disease With Andrew Vissing, MD
Andrew Vissing shares his clinical perspective and strategies to mitigate gaps in care and management for young adults with glomerular disease.
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The FDA granted Priority Review and accepted a New Drug Application for rusfertide to treat adults with polycythemia vera.

Mepolizumab Reduces Type 2 COPD Exacerbations Across Variable BEC Levels
A new study stratified patients by longitudinal BEC patterns to assess whether variability in eosinophil levels influences response.

Navepegritide, to be marketed as YUVIWEL, is the only FDA-approved treatment providing continuous CNP exposure over its weekly dosing interval.

The long-acting growth hormone is now indicated for children aged 2.5 years and older with Idiopathic Short Stature, born Small for Gestational Age, or Noonan Syndrome.

These new data from the OLYMPIA open-label extension study highlight long-term safety and efficacy findings on nemolizumab (Nemluvio).

Ross Milner, MD, discusses rising vascular complexity, advanced imaging and AI, and the team-based strategies driving durable aortic and limb salvage outcomes.

Panelist member explains new ASH guidelines aim to improve early diagnosis of AL amyloidosis with blood, urine, and biopsy testing.

Manreet Kanwar, MD, outlines advances in heart failure care, rising medication complexity, and the need for integrated, patient-centered systems.

AAAAI 2026 showcases high-impact clinical trials and innovative sessions, 5 of which are highlighted below.

David Rubin, MD, discusses rapid advances in IBD care, new therapies, multidisciplinary models, and the push toward precision GI medicine.

Parent company Eli Lilly has released full data from ACHIEVE-3, indicating superior weight loss and A1C reductions with orforglipron 12 mg and 36 mg.

The supplemental New Drug Application submission comes as a result of positive phase 3 data from the CORE and CORE2 trials or olezarsen in 2025.

Claims study suggests dry powder and soft mist COPD inhalers cut exacerbations versus MDIs, offering greener care without added safety risks.

The FDA has approved proprietary desmopressin oral solution formulation ET-600 for the treatment of central diabetes insipidus in children.

Vanda Pharmaceuticals announced the FDA's acceptance of imsidolimab's Biologics License Application for the treatment of GPP.

FDA approves dupilumab for allergic fungal rhinosinusitis, supported by phase 3 LIBERTY-AFRS-AIMS data showing reduced symptoms and corticosteroid or surgery use.

HCPLive speaks with Mark Lebwohl, MD, about recent data on those with psoriasis and obesity or overweight treated with ixekizumab (Taltz) and tirzepatide (Zepbound).

The list price of all 3 semaglutide drugs will be lowered to $675, marking a reduction of roughly 50% and 35% for Wegovy and Ozempic, respectively.

In a phase 2 trial in Chinese people with overweight or obesity, UBT251 led to mean weight loss of up to 19.7% (-17.5 kg) after 24 weeks.

An audio recap of the top 5 stories in healthcare news from the week of 02/15-02/21.

Seralutinib did improve 6-minute walk times and biomarkers, especially in patients with higher-risk disease.

Luspatercept met primary endpoints in transfusion-dependent and non–transfusion-dependent alpha-thalassemia.

This approval of the Allurion Gastric Balloon System, incorporating the Allurion Smart Capsule, is indicated for weight loss management for those with obesity.

The phase 3 REDEFINE 4 trial saw CagriSema achieve 23% weight loss, but fail to demonstrate noninferiority to tirzepatide in patients with overweight or obesity.

The FDA has granted both designations to TSRA-196, an in vivo gene editing program from Tessera Therapeutics, for the treatment of PiZZ alpha-1 antitrypsin deficiency.



























































































