Connor Iapoce

The January 2023 ophthalmology month in review features modifications in age-related macular degeneration risk, links between ophthalmic disease and quality of life, and complications during cataract surgery.

In a Dutch population, greater sedentary behavior was associated with an increased risk of DED, but data suggest the association was only significant for those with less than recommended physical activity.

Real-world data suggest nAMD eyes can extend injection intervals by switching to brolucizumab from other anti-VEGF therapies, while maintaining vision and reducing CMT.

Two-year data suggest the average cost of aflibercept monotherapy was approximately $26, 500 compared with approximately $14, 000 for the bevacizumab-first group in eyes with center-involved DME.

The FDA and CDC are urging the immediate discontinuation of EzriCare Artificial Tears as they investigates a multistate cluster of potential bacterial contamination.

The biologic from Amgen and AstraZeneca was approved for self-administration in a pre-filled, single-use pen for patients aged 12 years and older with severe asthma.

The geographic range of practitioner to million persons has increased since 2007, with disparities in practitioner distribution associated with lower socioeconomic status.

The statement suggests PCI without surgery on site is as safe as PCI at centers with on-site surgery across randomized controlled trials, observational studies, and international experiences.

Sintilimab plus IBI305 showed a significant improvement in objective response rate, time to response, duration of response, and depth of response in unresectable HCC versus sorafenib.

An analysis of the UK Biobank suggests individuals with celiac disease had an incidence rate of 9.0 CVD cases per 1000 person years compared with 7.4 per 1000 person years in people with no celiac disease.

The January 2023 endocrinology month in review features coverage of the FDA’s approval of bexagliflozin, news surrounding semaglutide, and the introduction of an expert-led, diabetes-focused podcast to HCPLive Endocrinology.

New data from the AHA 2023 Statistical Update suggest more people died from cardiovascular-related causes in 2020 than in any year since 2003.

The risk of diabetes was reduced by approximately 50% in both the vigorous and moderate aerobic exercise groups compared with the nonexercise group.

A lower DME resolution rate was associated with a thicker baseline CST and better baseline best-corrected visual acuity in eyes treated with aflibercept.

A sugary drinks tax in England may have prevented over 5,000 cases of obesity a year in older girls, but had no significant association with obesity levels in year six boys or younger children.

A ED screening program identified a substantial number of patients with undiagnosed prediabetes and T2D or undermanaged disease, particularly racial and ethnic minorities.

Although no incidence trends were observed in a German cohort, the data indicate patients with ILD-RA have received more biological/targeted synthetic DMARDs in recent years.

The association was generally consistent across the subgroups of age, sex, use of systemic corticosteroids, and comorbidity levels in the population-based cohort.

An analysis of the Jackson Heart Study reports economic food insecurity as a risk factor for incident CHD and incident HFrEF, independent of socioeconomic measures and traditional CV risk factors.

Rurality was associated with an increased risk of HF among women and Black men, which persisted after adjustment for cardiovascular risk factors and socioeconomic status.

Participants in the Tromsø study with both obesity and moderately high/high waist circumference at baseline had increased odds of being frail compared with those in the normal range.

Repeated injections with preoperative povidone-iodine application was associated with reduced meibomian gland loss, increased tear volume, and reduced signs of inflammation.

Results from the ACTIVE-AF trial indicate participation in an exercise-based intervention reduced arrhythmia recurrence and improved symptom severity among patients with AF.

Men in the highest quartile of PDE-5i exposure had the lowest incidence of MACE and overall mortality compared to the lowest exposure quartile.

Eyes treated with pegcetacoplan showed a significantly slower GA lesion progression rate compared with sham, and slower growth rate toward the fovea.

Factors including age and disease activity influenced the selection of JAK inhibitors over biologic disease-modifying antirheumatic drugs for RA patients beginning therapy.

6-year results from the LiGHT trial suggest SLT is a safe treatment for eyes with open-angle glaucoma and ocular hypertension, providing drop-free IOP control.

A systematic review and meta-analysis of 30 studies indicates a favorable effect of TNF inhibitors on surrogate markers for CVD risk.

Stroke symptoms that disappear in under an hour need emergency assessment to help prevent a full-blown stroke. A new scientific statement from the AHA provides guidance and a standardized approach to evaluating people with suspected TIA, particularly in rural areas.

Each 1-SD increment in HDL-C level was associated with a 14% higher risk of fractures in cohort study of approximately 16,000 community-dwelling healthy adults.