February 21st 2024
After studying sweat metabolic changes, investigators noted significant effects in the metabolism of carbohydrates, amino acids, energy metabolism, the urea cycle, and metabolic pathways connected to oxidative stress due to OSA and the severity stage.
A new study found smoking affects serum leptin levels for patients with obstructive sleep apnea on positive airway pressure therapy. Serum leptin levels increased in 40% of active smokers with obstructive sleep apnea but did not increase in any of the non-smokers.
Certain craniofacial measurements identified by lateral cephalograms exhibit notable variations in patients with obstructive sleep apnea, providing potential indicators for early diagnosis.
Sleep quality and the absence of sleep apnea may play a crucial role in preserving cognitive function over time, emphasizing the significance of addressing sleep disturbances for overall brain health.
Disrupted sleep is prevalent among children and adolescents with Down syndrome and prompt diagnosis and management of the condition are crucial to ensure optimal health and well-being in this population.
CCDC3 has shown to repress inflammatory activity of TNF-alpha, a cytokine postulated involved in sleep regulation and MARCHF1 has shown to inhibit cellular insulin sensitivity and promotes NF-KB, with degree of activation positively correlating with OSA severity.
Risk factors for trouble sleeping identified, including female sex, former smoking, and diabetes, obstructive lung disease, daytime sleepiness, insomnia, nocturia, and/or snorting/gasping/breathing cessation during sleep.
In patients hospitalized with acute coronary syndrome and metabolic syndrome, obstructive sleep apnea was associated with an increased risk of major adverse cardiovascular and cerebrovascular events in women, but not in men.
The study evaluated how intranasal mometasone furoate affected sleep-disordered breathing symptoms and patient quality of life by comparing its efficacy to intranasal saline in the pediatric patients.