Obstructive Sleep Apnea

A late-breaking abstract from SLEEP 2024 shows the effect of mandibular devices on respiratory effort, and its overall impact on OSA.

An alternative device to CPAP shows clinical benefit and long-term patient adherence in new SLEEP 2024 trial data.

Topline data from the SURMOUNT-OSA studies provide insight into the effects of tirzepatide in OSA with obesity, with Lilly disclosing plans for a regulatory submission mid-year.

A new study found patients with a BMI of 32 to 35 have lower odds of responding to the hypoglossal nerve stimulation for OSA compared to patients with a lower BMI.

With limited CBTi-trained psychologists, investigators assessed the effectiveness of a self-guided digital CBTi as another option, so people don’t have to turn to pills.

After 5 years, laparoscopic Roux-en-Y gastric bypass cured OSA in 55.1% of patients, and only 20% of patients still had moderate or severe OSA.

After observing for sex differences, plant-based diet indices were associated with lower odds of OSA risk in males than females.

A new study found the odds of gout were 2.65 times greater in patients with OSA than in patients without OSA.

A new study for women with ≥ 4 hours a day of sedentary behavior had an increased risk of OSA but not for women with < 4 hours of sedentary behavior.

Sleep apnea prevalence in cardiology patients was similar to the rates in patients with heart failure., and sleep apnea prevalence in cardio-oncology patients was the same or greater than other traditional risk factors.

In a new study, nearly a third of participants with OSA reported using > 3 coping strategies, but participants without OSA reported never using > 3 coping strategies.

A multivariable analysis showed that, in a cohort of asthma patients, being at high risk for OSA, women, having uncontrolled rhinitis, and GINA steps 4-5 were linked to uncontrolled asthma.

After studying sweat metabolic changes, investigators noted significant effects in the metabolism of carbohydrates, amino acids, energy metabolism, the urea cycle, and metabolic pathways connected to oxidative stress due to OSA and the severity stage.

Compared to individuals without OSA and regular sleep, individuals with OSA combined with severely irregular sleep had the highest odds of hypertension, according to a new study.

A new study found smoking affects serum leptin levels for patients with obstructive sleep apnea on positive airway pressure therapy. Serum leptin levels increased in 40% of active smokers with obstructive sleep apnea but did not increase in any of the non-smokers.

The FDA issued a warning about the DreamStation 2 CPAP Machine, which is used to treat obstructive sleep apnea, due to reports of the device overheating and leading to fires, smoke, and burns.

A new study found a 35% prevalence of newly diagnosed obstructive sleep apnea in patients with lingering COVID-19 symptoms of fatigue or sleepiness.

The study presents a machine learning algorithm utilizing ECG data during CPAP titration that can effectively forecast sleep apnea events.

Certain craniofacial measurements identified by lateral cephalograms exhibit notable variations in patients with obstructive sleep apnea, providing potential indicators for early diagnosis.

Knowing how patients with different endotypes respond to CPAP therapy can help physicians predict treatment efficacy and tailor individualized treatment plans, according to results.

Sleep quality and the absence of sleep apnea may play a crucial role in preserving cognitive function over time, emphasizing the significance of addressing sleep disturbances for overall brain health.

Disrupted sleep is prevalent among children and adolescents with Down syndrome and prompt diagnosis and management of the condition are crucial to ensure optimal health and well-being in this population.

Lemborexant was statistically similar to placebo on both day 1 and day 8 for any group in latency to persistent sleep, but superior in sleep efficiency and wake after sleep onset.

CCDC3 has shown to repress inflammatory activity of TNF-alpha, a cytokine postulated involved in sleep regulation and MARCHF1 has shown to inhibit cellular insulin sensitivity and promotes NF-KB, with degree of activation positively correlating with OSA severity.

Pediatric sleep conditions remain understudied.

With a high rate of lost patients, effective treatment is compromised regardless of the success rendered by unattended portable sleep studies, investigators explain.

Risk factors for trouble sleeping identified, including female sex, former smoking, and diabetes, obstructive lung disease, daytime sleepiness, insomnia, nocturia, and/or snorting/gasping/breathing cessation during sleep.

The team aimed to examine the impact surgical treatment of obstructive sleep apnea had on periodic limb movement index in pediatric patients.

The results show melatonin levels or phases relative to clock time were not different between healthy individuals and patients with obstructive sleep apnea.

The rate of sleep apnea is greater in patients with bipolar disorder and depression.