Peer Exchange

Manesh R. Patel, MD; Payal Kohli, MD, FACC; John M. Flack, MD, MPH, FAHA, FASH, MACP, CHS, and C. Michael Gibson, MS, MD, explore the challenges and evolving management strategies for resistant hypertension, including medication adherence, comorbidities like CKD, traditional and novel drug mechanisms like aprocitentan, and the importance of accurate blood pressure measurement, while emphasizing the critical role of the endothelin pathway and comprehensive treatment approaches.

Panelists discuss how a multidisciplinary approach, early diagnosis, and emerging therapies are essential in managing Familial Chylomicronemia Syndrome (FCS)to prevent acute pancreatitis and mitigate long-term cardiovascular risks.

Panelists discuss how comprehensive cardiovascular disease management requires integrating screening protocols, risk assessment, and targeted interventions across the lifespan, from pediatric lipid testing through adult treatment strategies, while addressing barriers to care and leveraging both established and emerging therapeutic options.

Panelists discuss how addressing the gaps in screening, diagnosis, and treatment can significantly improve outcomes for patients with chronic kidney disease (CKD) in the context of type 2 diabetes.

This discussion provides an in-depth overview of Primary Biliary Cholangitis (PBC), covering pathophysiology, clinical presentation, diagnostic approaches, disease progression, management strategies—including first- and second-line therapies—and recent advances in PPAR agonist treatments to guide optimal care for patients.

Panelists discuss how to effectively diagnose and manage chronic spontaneous urticaria, highlighting the importance of personalized treatment approaches and the exploration of emerging therapies to improve patient outcomes.

Panelists discuss how evolving treatment strategies and improved diagnostic approaches can enhance the management of Cchronic Sspontaneous Uurticaria (CSU), ultimately aiming to improve patient outcomes and quality of life.

Panelists discuss how early diagnosis and the utilization of systemic Janus kinase inhibitors are crucial in the effective management of alopecia areata, highlighting the impact of disease severity and patient experiences on treatment strategies.

Raj Chovatiya, MD, PhD, MSCI; George Han, MD; Elizabeth (Lisa) Swanson, MD; and Peter Lio, MD, explore the latest advances in oral systemic treatments for atopic dermatitis, including the use and long-term safety of oral JAK inhibitors, strategies for switching therapies, and navigating treatment breaks.

Medical experts discuss hypercortisolism in the diabetes landscape.

A panel of experts on atopic dermatitis review clinical trial data and discuss how treatment advances are improving patient-reported outcomes and elevating the standard of care.

A panel of experts on iron deficiency anemia has a comprehensive discussion on the clinical utilization of intravenous iron, highlighting available products and clinical practices on administration and monitoring.

Led by Gordon K. Lam, MD, FACR, a panel of medical experts will provide insights surrounding treatment and management for patients diagnosed with rheumatoid arthritis.

Pamela Kushner, MD, FAAFP; Nancy Reau, MD; Arun B. Jesudian, MD, and Kimberly Brown, MD, discuss diagnosing hepatic encephalopathy (HE), strategies for preventing the progression of cirrhosis, the current standard of care for HE management, and provide guidance to support primary care clinicians in effectively treating patients with HE in the outpatient setting.

Experts on chronic obstructive pulmonary disease (COPD) have a comprehensive discussion on treatment practices, with a focus on emerging pathways and the role of type 2 inflammation in patients with the disease.

A panel of experts discuss simplified treatment approaches for HIV, highlighting the role of the primary care and advanced practice provider, the importance of early treatment initiation, and ways to manage drug resistance.

Nicole Chase, MD, leads a panel of medical professionals highlighting critical aspects of asthma exacerbation and treatment management.

Medical experts provide a comprehensive approach to proactively treathigh levels of LDL, highlighting lesser-known therapies and trials that could benefit the field and mitigatehyperchlolesteromia.

Hanford Yau, MD, Ralph DeFronzo, MD, Pam Kushner, MD, Honey East, MD, and Christopher Lucci, MD, discuss the challenges of managing patients with resistant diabetes, emphasizing key strategies for identifying and treatingunderlying hypercortisolismthat leads to resistant diabetes.

Experts extensively review the array of psoriasis treatments, from topicals to biologics, exploring the landscape of IL therapies and their enhanced safety and efficacy compared to previous agents. The physicians also highlight how common comorbidities may impact on treatment decisions.

Different clinical specialists in the management of inflammatory diseases discuss the role of adalimumab biosimilars in the treatment of their patients.

A panel of ophthalmologists and vitreoretinal specialists discuss treatments for retinal diseases, specifically neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME). Experts highlight two new therapies, aflibercept 8 mg and faricimab, and how the addition of biosimilars and gene therapy are changing the landscape of care for the better.

Leading dermatologists discuss management of psoriasis in patients with skin of color, including disease presentation, cultural stigma and its impact on patient’s quality of life. They also share recently presented and published data, highlighting use of biologics for treatment of psoriasis in patients with skin of color.

In an upcoming Peer Exchange program entitled “Dual-Orexin Receptor Antagonists for Treatment of Insomnia” Dr Paul Doghramji will moderate a conversation with physicians about this class of agents for treatment of insomnia and discuss other therapeutic advancements in the field.

Expert panelists discuss the need for early introduction of biologic therapy in Crohn’s disease, therapeutic targets in CD management, and advanced therapies for more effective CD treatment.

Expert cardiologists discuss the role of non-statin therapies in lowering LDL cholesterol, recent clinic trial data on who can benefit, as well as how to implement these agents into your clinical practice.

Expert dermatologists discuss the use of Janus kinase (JAK) inhibitors for the treatment of atopic dermatitis (AD). They review the nuances of currently approved JAK inhibitors, share treatment considerations for AD, and discuss utilizing JAK inhibitors in clinical practice.

A straight forward approach to taking care of patients with Hepatitis C. Experts in the field are offering a simplified overview for new providers on the who, what, where and when of hepatitis C care, as well as practical tips for treatment implementation

Dermatologists discuss the burdens, unmet needs, and emerging treatment options for patients with seborrheic dermatitis, offering clinical insights on therapeutic approaches and the importance of patient-centered care.