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Vitamin D Could Cut Risk of Progression to Type 2 Diabetes in People with Prediabetes
February 7th 2023Leveraging data from the Tromsø study, the D2d study, and the DPVD study, a systematic review and meta-analysis concluded vitamin D supplementation could help reduce risk of progression to diabetes by 15% among people with prediabetes.
In T2D, SGLT2s Provide Greater CV Risk Reduction Than DPP-4 Inhibitors
February 7th 2023A new-user comparator study of adults with type 2 diabetes indicates use of SGLT2 inhibitors was associated with a 54% lower risk of hospitalizations for heart failure and a 15% lower risk of a modified MACE outcome compared to use of DPP-4 inhibitors.
Significant Decreases in Tophus, Double Contour Sign Observed in Patients With Gout Receiving ULT
Musculoskeletal ultrasound evaluated tophus size and double contour sign in lower extremity joints of patients with gout before and after initiating uric acid lowering therapy.
Data Show 74.7% Reduction in Varenicline Use for Nicotine Dependence After Chantix Recall
February 6th 2023It wasn't the unavailability of varenicline, but the inaccessibility, that perpetuated the reduced prevalence of prescriptions. Investigators speculated that patient, clinician awareness and concerns related to nitrosamine were contributing factors.
DECT Scoring System Proves to be a Noninvasive, Effective Tool for Gout Diagnosis
The DECT scoring system obtained excellent diagnostic performance for differentiating early-stage gout from middle-stage gout, with sensitivity, positive and negative predictive values, and specificity all achieving an accuracy of > 85%.
Anthracycline Use Linked to More than Doubling in Heart Failure Risk, Study Finds
February 6th 2023An analysis of data from the Rochester Epidemiology Project suggests those with breast cancer or lymphoma who received treatment with anthracycline therapy experienced a more than doubling in risk of heart failure compared to controls without cancer.
Investigators Identify Risk Factors for Fatty Liver of Living Donors
While 20% of the patient population had a Fib-4 index greater than 1.3, including 1 case of a Fib-4 index greater than 2.67, the investigators did not identify a significant increase in Fib-4 index in patients with fatty liver compared to those who did not develop fatty liver.