Gastroesophageal Reflux Disease (GERD)

From a novel acne cream to a breakthrough depression drug, a half-dozen agent decisions are coming through in the coming 6 months.

The results also show 10.3% of the patients with celiac disease that was histopathological confirmed were seronegative to Anti-TtG-IgA, but seropositive to anti-DGP-IgA and/or Anti-DGP-IgG.

From new ACG GERD guidelines to the efficacy of colonoscopies, our latest issue addresses topics changing practice and stirring conversation.

A review of changes to clinical, dietary and screening strategies for patients with GERD.

Nearly half of patients treated with vonoprazan 10 mg and 20 mg achieved more 24-hour heartburn free days compared to participants treated by placebo.

The median DeMeester score decreased from 32-3.7 following LTF.

The new recommendations call for posterior partial fundoplication over total posterior or anterior 90° fundoplication in adult patients with GERD and anterior >90° fundoplication as an alternative.

Both post-transplant PPI and histamine-2 receptor antagonist use were independently associated with reduced risk of 1-year mortality.

DASH diet was inversely associated with NAFLD risk, independent of BMI changes.

The long-term efficacy of fundoplication surgery has not previously been explored for the management of the symptoms of GERD.

In data presented at AAD, investigators found increased odds of GERD in patients with rosacea compared to a control group without rosacea.

The guidelines focus on diagnosing and screening for Barrett’s esophagus and esophageal adenocarcinoma.

There is a significant direct correlation between post-reflux swallow-induced peristaltic wave index and mean nocturnal baseline impendence for patients with GERD.

The endomina system can be affixed to various testing standard endoscopies for a bendable therapeutic channel.

Diagnosing patients with classic GERD symptoms such as heartburn and regurgitation call for an 8-week trial of empiric proton pump inhibitors once daily prior to a meal.

Taste scores were significantly correlated with depression scores for both patients with irritable bowel syndrome and functional constipation.

Despite conflicting data, investigators form Spain found that gastroesophageal reflux disease and asthma are bidirectional, with each disease exacerbating each other.

Vonoprazan has shown more potent acid inhibitory effects than PPI.

New data has investigators caution against the discontinuation of ulcerative colitis treatment, due to threat of relapse.

A cohort assessment shows a 57% increased risk of pediatric asthma development among children given PPIs to treat gastrointestinal tract disorders.

Investigators look at persistent symptoms for GERD patients taking proton pump inhibitors.

In a comparison, investigators find that surgery is more successful in treating GERD patients who do not respond to protein pump inhibitors.

Recent clinical assessment of gastroesophageal reflux disease has linked it to an inflammatory response triggered by cytokines.

Who is the best candidate for invasive treatment in the GERD population?

How increasing obesity rates have affected the prevalence of GERD and re-prioritized first-line care.

Why delving into the symptoms of the most at-need patients is critical for care.

GERD patients have fewer postoperative complications with LARS than with OARS.

Heartburn drugs like Prilosec and Nexium might alleviate acid reflux, but could raise the risk of severe stomach infections.

Atop already surprising studies that linked their daily use with increased risk of kidney failure, new data has emerged that shows they may also contribute to weakening of the bones.

Gastroesophageal reflux disease (GERD) has long been thought to result from built up stomach acid damaging the lining of the esophagus.