Pain Management

Impact of exercise on pain perception suggests potential of physical activity in pain management. Athletes seem to have significantly higher pain tolerance than normally-active people.

The majority of patients with long-bone fractures receive inadequate pain medication in the emergency department, and disparities in management exist.

For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness and visual analog score) (DAS28-P) at baseline are predictive of less improvement in pain at one year.

A variety of pre-, intra-, and postoperative factors contribute to increased length of stay (LOS) for patients who undergo level 1 minimally invasive (MIS) transforaminal interbody fusions (TLIF) spine surgery.

For patients with acute or persistent low back pain, pain and disability improve in the first six weeks of treatment, but low-to-moderate pain and disability tend to persist at one year.

Smoking cannabis is associated with a reduction in spasticity for patients with multiple sclerosis (MS).

Overweight and obese patients with rheumatoid arthritis (RA) have lower all-cause and cardiovascular mortality, but have substantially increased risks of comorbidities, medical costs, and reduced quality of life compared with normal-weight RA patients.

One-third of U.S. adults with physician-diagnosed arthritis report having anxiety or depression, with anxiety more prevalent than depression.

Pain catastrophizing, in particular ruminating about pain, has an indirect effect on clinical pain severity and pain-related interference, through sleep disturbance.

Obesity is linked with the risk of developing rheumatoid arthritis (RA), and seems to have contributed to the recent increase in incidence of the condition.

For patients with fibromyalgia, spatial extent of pain, pain aftersensation, and negative mood account for approximately one-third of the variance in clinical pain, but sleep measures do not significantly predict pain.

Patients with celiac disease or inflammatory bowel disease (IBD) and those self-classified with gluten sensitivity (GS) have increased prevalence of migraine.

Heroin-addicted patients treated with methadone or buprenorphine have a heightened sensitivity to pain, and the hyperalgesia does not change over the course of treatment.

Botulinum toxin A provides a modest benefit for patients with chronic migraine headaches and chronic daily headaches, compared with placebo.

Few patients with acute low back pain (LBP), with or without sciatica, declare sick leave; however, approximately half have one or more recurrences and a considerable proportion experience chronic pain six months or longer after the initial episode.

Frequency and severity of migraine attacks can be reduced using Several pharmaceutical treatment strategies that are available.

Pain coping strategies can significantly impact the physical symptoms and psychological distress experienced by patients with systemic lupus erythematosus (SLE).

Patients with depression are significantly more likely to have peripheral artery disease (PAD) and to have a PAD-related event.

Individuals suspected of having multiple sclerosis (MS) are less likely to be diagnosed with clinically definite disease if they soon start treatment with interferon (IFN) β-1a.

Omega-3 (ω-3) fatty acid supplements do not improve disease activity in patients with relapsing-remitting multiple sclerosis (MS).