Phase 3 Data on Brilaroxazine for Schizophrenia with Larry Ereshefsky, PharmD
In an interview with HCPLive, Larry Ereshefsky, PharmD, discussed the phase 3 RECOVER trial assessing brilaroxazine at 50 mg and 15 mg for acute schziophrenia.
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Patients Have Lower Mortality When Treated by Female Physicians
A new study found female patients (8.15%) had a lower mortality rate when treated by female physicians than male physicians (8.38%).
Middle Age and Older Adults Perceive “Old Age” Begins Later Than a Decade Ago
A new study found the perceived onset of old age rose nearly 3 years from 1911 to 1953.
1 in 3 Older Adults Reported Using an Alternate Health Care Site
A poll found people were more likely to use alternate health care sites if they were women, aged 50 – 64 over 65 – 80 years, and had a household income of < $60,000.
More Than Half of RA Patients Achieve Remission After Upadacitinib 15 mg
An extension study showed upadacitinib 15 mg and 30 mg for rheumatoid arthritis continues to be favorable, with many patients achieving remission.
Pharmacy-Based Intervention Linked to Reduced Proton Pump Inhibitor Overuse
A new study found an intervention targeting proton pump inhibitor overuse was linked to an absolute reduction of 7.3%.
2022 Spike in “Deaths of Despair” Among Black Population Surpasses White People
A recent study found Black individuals had a sharp increase in midlife deaths from suicide, drug overdose, and alcoholic liver disease after 2015.
Secukinumab 300 mg May Improve PsA or Active Psoriasis More Than 150 mg
A pooled analysis revealed a loading-dose regimen, especially for patients receiving secukinumab 150 mg for PsA, increases the odds of disease improvement.
Insight on the Promising 52-Week KarXT Data with Rishi Kakar, MD
In an interview with HCPLive, Rishi Kakar, MD, discussed the positive long-term xanomeline-trospium data from EMERGENT-4.
PTSD Emotional Numbing Impacts Intensity of Neutral to Negative State Shifts
A new study found individuals with PTSD face rapid transitions between neutral and negative emotional states.
Children with Sleep Disorders Have Double the Odds of Increased Health Care Usage
A new study explored increased health care utilization of children among several specific sleep disorders, race, and age.
Delayed Appendicitis Diagnosis Linked to Increased Hospital Care Costs
Patients with a delayed appendicitis diagnosis had 1.23 times increased hospital care costs, and Black patients had a greater increased cost than White patients.
Sunny Rai, PhD: “I” Language Markers Do Not Detect Depression in Black Individuals
In an interview with HCPLive, Sunny Rai, PhD, shed light on a new study regarding how an AI model failed to detect depression in Black individuals.
Secukinumab and Sandoz Adalimumab Have Similar Outcomes When Treating r-axSpA
A new study showed secukinumab was not superior to Sandoz adalimumab (SDZ-ADL; TNF inhibitor) in terms of similar low rates of radiographic progression and safety profiles.
MRI Treat-to-Target Strategy Fails to Help RA Patients Reach Remission
A study found MRI treat-to-target strategy does not help bring RA patients to remission, even when also targeting the absence of osteitis alongside clinical remission.
Extending Postpartum Medicaid Linked to Increased Perinatal Mental Health Care
A new study found extending postpartum Medicaid from 60 days to 12 months is linked to new mothers being more likely to seek mental health care for perinatal mood and anxiety disorders.
IFX-dyyb Boosts Rheumatoid Arthritis Outcomes in 6 Months
A new study provides insight into the effectiveness of IFX-dyyb in a real-world US population of RA patients, showing how the biosimilar compares to other treatments.
Single Dose of Esketamine After Childbirth Reduces Postpartum Depression
A new study found a single low dose of esketamine given shortly after childbirth reduced major depressive episodes at 42 days postpartum by about 3 quarters.
Adverse Effects of Therapeutic Psilocybin Are “Tolerable” and Resolve in 48 Hours
Patients on psilocybin for depression or anxiety reported tolerable adverse events, including headache, nausea, anxiety, dizziness, and elevated blood pressure.
Patients with BMI Over 32 Respond Less to Hypoglossal Nerve Stimulation for OSA
A new study found patients with a BMI of 32 to 35 have lower odds of responding to the hypoglossal nerve stimulation for OSA compared to patients with a lower BMI.
Acetaminophen Use During Pregnancy is Not Linked to a Child’s Risk of Autism or ADHD
Sibling control analyses showed acetaminophen use during pregnancy was not associated with an offspring’s risk of autism, ADHD, or intellectual disability.
“I” Usage Predicts Depression Severity in White but Not Black Individuals
A study using machine learning models found “I” usage on Facebook posts does not predict depression severity in Black individuals.
KarXT Effective in Improving Schizophrenia Symptoms at 52 Weeks
EMERGENT-3 trial showed xanomeline-trospium was effective in improving schizophrenia symptoms at 52 weeks, for participants who took either placebo or KarXT in acute trials.
People with Dementia and Their Care Partners Have an Increased Loneliness Risk
The study highlights how the experience of loneliness for care partners of people with dementia changes relationship roles throughout the dementia trajectory.
Medication Post-Alcohol-Related Hospitalization Discharge Reduces Death Risk
A new study showed how taking alcohol use disorder medication following an alcohol-related hospitalization discharge was linked to a reduction in return to hospital in 30 days.
Smartphone App Accurately Detects Frontotemporal Lobar Degeneration
A trial demonstrated the reliability and validity of a smartphone app’s capability of detecting frontotemporal lobar degeneration.
MDMA-Assisted Therapy for PTSD Is Backed by Positive Data
Lykos Therapeutics announced the FDA accepted its NDA for MDMA-assisted therapy for individuals with PTSD on February 9, 2024, backed by phase 3 data showing the drug’s efficacy.
International Working Group Releases First Guideline for Osteoporosis in Men
The first guideline for the management of osteoporosis in men provides recommendations for diagnosis, monitoring, and treatment.
Sleep Month in Review: March 2024
This sleep month in review highlights the 6 top sleep pieces in March, from FDA news, topline data, and pieces exploring how daylight savings and long COVID impact sleep.
First Patient Randomized in Phase 2 Trial to Assess Efficacy of NBI-1070770 for MDD
Although still recruiting, the first patient was randomized to receive NBI-1070770 for major depressive disorder in a phase 2 trial assessing efficacy, safety, and tolerability.