Each year, the American Heart Association's (AHA's) Scientific Sessions is the organization's largest yearly gathering of healthcare professionals and researchers in the field of cardiovascular disease and stroke. Providing 5 days of comprehensive education with more than 4000 presentations by world leaders in cardiovascular disease, the AHA 2014 Scientific Sessions featured the results of landmark and long-awaited clinical trials.
Worsening renal function over time is associated with poorer outcomes in patients with acute and chronic HF. Although this association is established in patients with reduced ejection fraction, there are no data about the relationship between WRF and outcomes in HF patients with preserved ejection fraction.
While various behavioral and pharmacologic agents have proven to be effective and safe for continued smoking cessation, a combination of varenicline and nicotine replacement (NRT) with transdermal patches has not been shown definitively to be more efficacious than varenicline alone. In the framework of a randomized clinical trial (RCT), the present study evaluates whether a combination of varenicline with NRT improved smoking cessation rates and abstinence duration compared with varenicline alone.