Jonathan Barratt, PhD, FRCP, and Brad Rovin, MD, review the driving factors of disease progression of IgAN (immunoglobulin A nephropathy).
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Preparing for a New Era in IgAN Treatment: Staying up to Date on the Latest Developments in Targeted Immune-Modulating Therapies
Experts in nephrology take a deep dive into the latest developments in immune-modulating therapies in IgA (immunoglobulin A) nephropathy. They discuss the different mechanisms of actions and the most recent clinical trial data, as well as take a look into the future on how to incorporate novel therapies into clinical practice once they become available.
Preparing for a New Era in IgAN Treatment: Staying up to Date on the Latest Developments in Targeted Immune-Modulating Therapies
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Jonathan Barratt, PhD, FRCP, and Brad Rovin, MD, provide an overview of the foundational therapies approved for treatment of IgAN and their functions.
Experts in nephrology focus on the need for an agent which inhibits the pathogenesis or interrupts disease progression of IgAN.
Brad Rovin, MD, outlines the use of complement inhibitors as an alternative to systemic glucocorticoids for the treatment of IgAN.
Nephrology experts explore the role of dual inhibition of BlyS and APRIL in the treatment of IgAN, and how this can impact disease pathogenesis.
Jonathan Barratt, PhD, FRCP, and Brad Rovin, MD, review clinical trials for new and emerging treatments for IgAN, highlighting atacicept and telitacicept.
Drs Jonathan Barratt and Brad Rovin comment on clinical trial data regarding the use of povetacicept for the treatment of IgAN.
Jonathan Barratt, PhD, FRCP, and Brad Rovin, MD, discuss the future of IgAN treatment, highlighting the BlyS/APRIL axis.
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