New research on the potential anti-H. pylori and anti-inflammation in vivo effects of two lactobacillus strains from the human stomach may indicate a possible new treatment for H. pylori-associated diseases.
effects of two lactobacillus strains from the human stomach may indicate a possible new treatment for
World Journal of Gastroenterology
, the researchers divided 40
Lactobacillus fermenti (L. fermenti)
proton pump inhibitor and antibiotics triple-treated group, a
-treated group, a
-treated group, and a normal saline control group. Ten uninfected mice were included as a blank control group.
According to the study results, published in the mice into four groups: a
The researchers wrote, “Histopathologic evaluation showed significant release of mucosal inflammation in gastric antrum and gastric body in
treated groups and triple treated group.
eradication rate in both
treated groups and triple treated group were higher than normal saline control group.
treated groups and triple treated group showed significant decrease of
Rapid urease tests, Giemsa staining, and bacterial culture were used to identify
infection, and the colonization of these bacteria “was assessed in bacterial density score and gastric inflammation was assessed in histological score.” The researchers used fluorescent probe to colonize
Both actobacillus strain
) showed “significant” activity against
was found to have “more efficient antagonistic activity
,” with efficacy that was close to the rate produced by standard triple therapy.
New research on the potential