RN Practice Poll #2: MTX Plus Anti-TNF Fails in RA. What Next?


Last week's poll asked what you'd do for a rheumatoid arthritis patient unhelped by methotrexate. That strategy has failed too: What next? Weigh in here with your best choice.

Thank you for joining the weekly Practice Poll, our effort to gauge current practice regarding unresolved issues in rheumatology.

Last week's poll considered what to do after a methotrexate failure in RA. There's still time to check in and enter your opinion, if you haven't yet done so. This week we move along with the same patient. If that strategy fails, what will you try next?

See also:

RN Practice Poll #1: Your Strategy After MTX Fails in RA


In an RA patient, after the first anti TNF + MTX fails, what do you change to?

Another anti-TNF
Tocilizumab (Actemra) IV or subQ
Abatacept (Orencia) IV or subQ
Rituximab (Rituxan)
Add leflunomide (Arava)
Switch to oral JAK inhibitor
Stop anti-TNF and add hydroxychloroquine and sulfasalazine
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