SPRINT: What Now?


How many US adults are considered eligible for SPB equal to/less than 120 mm Hg? What about those who aren't?

In the 2015 SPRINT (Systolic Blood Pressure Intervention Trial), reaching a target systolic blood pressure (SBP) of <120 mm Hg was associated with lower cardiovascular disease (CVD) risk compared with reaching an SBP goal of <140 mm Hg. The latter value had long been held as an appropriate goal for patients with hypertension.

In this Medical News Minute, produced exclusively for Practical Cardiology, Dr Bobby Lazzara reviews a study published in the February issue of the Journal of the American College of Cardiology that sought to estimate the prevalence and number of US adults meeting SPRINT eligibility criteria and to establish beyond that the broader population to whom the SRPINT study results could be generalized.

Approximately 7.6% of US adults and 16.8% of adults with treated hypertension met the criteria. Note that adults excluded from the original SRPINT trial included those with diabetes, history of stroke, proteinuria, heart failure, eGFR <20 ml/min/1.73 m2, or receiving dialysis.

Source: Bress AP, Tanner RM, Hess R, et al. Generalizability of SPRINT results to the US adult population. J Am Coll Cardiol. 2016 Feb 9;67:463-72. doi: 10.1016/j.jacc.2015.10.037. Epub 2015 Nov 9


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