Amber N. Mitchell, MD

A recent review found that tonabersat, a novel benzoylamino benzopyran compound, is well-tolerated, but no better than placebo for migraine prophylaxis.

According to a recent systematic review, the prescient and short-term use of NSAIDs and opioids with pharmacological sensitivity to an individual's comorbidities may result in pain relief, improved functioning, and reduced vocational and avocational absenteeism.

Meta-analysis of clinical trial data on the use of antidepressants and anticonvulsants for the treatment of painful diabetic neuropathy indicates gabapentin is the most efficacious agent for this condition, while the side effects associated with amitriptyline make it the least tolerable treatment option evaluated in the study.

Study shows that somatization and low job security are independently associated with low back pain prevalence.