Authors
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Wellsphere Blogger Flap Raises Questions about Content OwnershipIt started with an e-mail to thousands of health bloggers from Dr. Geoff Rutledge, Chief Medical Information Officer at the health website Wellsphere.
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White-coat hypertension and progression to home hypertensionOur study aimed to clarify whether white-coat hypertension represents a transient state in the development of hypertension outside medical settings. We followed up 128 subjects with white-coat hypertension and compared their risk of progression to home hypertension with that of 649 sustained normotensive subjects. After 8 years of follow-up, subjects with white-coat hypertension had an approximately 3-fold higher risk of eventually manifesting home hypertension. We concluded that patients with white-coat hypertension should be carefully monitored.
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Hedgehog Signal Inhibition Hope or Hype?Once a human malignancy metastasizes, currently available cytotoxic chemotherapy is usually palliative. While conventional chemotherapy regimens are associated with objective tumor regression, this only occurs in a minority of patients.
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Cultural Divide? How Crossing it Made Me a Better DoctorHer older Caucasian patients figured she was a nurse.
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Automating the Documentation and Coding ProcessAccurate documentation and coding is essential for efficient billing and reimbursement.
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Regression of electrocardiographic left ventricular hypertrophy and heart failure in hypertensive patientsPrior studies have shown an association between heart failure and the presence of hypertension and left ventricular hypertrophy (LVH). We investigated the relationship between regression of electrocardiographic (ECG) LVH by Cornell product with antihypertensive regimens and new-onset heart failure in subjects with hypertension and baseline LVH.
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Obesity and cardiovascular risk in hypertensive patients with left ventricular hypertrophyThe observed relationship linking obesity, severity of hypertension, and increase in cardiovascular risk was traditionally thought to emanate from the increase in circulatory volume, persistently increased systemic resistance from obesity, and clustering of major cardiovascular risk factors (eg, hypercholesterolemia and diabetes mellitus) among obese patients.
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Concerns about Pain Guidelines: When Strong Claims Follow from Weak EvidenceThe development of clinical medical-practice guidelines is a difficult and arduous process. Experts in various disciplines volunteer many hours of their time for medical research reviews and analyses and meetings with fellow guidelines-panel members, and painstakingly writing and reviewing the final report. However, there are many concerns about the quality of medical research serving as a basis for those guidelines.
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Hypertension in the elderlyMore important than the choice of pharmaceutical agent in the treatment of elderly hypertensive patients is the achievement of goal blood pressure. Low-dose diuretics, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and calcium channel blockers are equally effective in reducing cardiovascular end points. Most patients will require 2 or more drugs to achieve target blood pressure, and physicians should feel comfortable prescribing 3 to 4 agents to a significant proportion of patients.
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The Academy: April 2007The Academy delivers the latest news on biotechnology and oncology research, providing a link between the clinical world of cancer care and the university researchers who are pushing farther into knowledge and discovery. In this issue: 1) Wellcome Trust Sanger Institute 2) Memorial Sloan-Kettering Cancer Center 3) University of Leicaster (UK) 4) Purdue University 5) St. Jude Children's Research Hospital 6) MESA+ Institute for Nanotechnology of the University of Twente, Enschede, The Netherlands
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Colorectal Surgery: Ischemic Colitis is Highest RiskReadmission because of complications from colorectal surgery has been a challenge for surgeons.
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Tackling Xenophobia: Are We There Yet?The mental health effects of xenophobia can have far-reaching consequences for children and adolescents.
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Coronary risk and statin use in the elderly: Discordance between disease burden and treatmentIn the United States, 42% of acute myocardial infarctions (MIs) and more than 60% of deaths attributable to acute MIs occur in the 6.1% of the population 75 years of age or older.
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Physician Assistants Deserve More Pay than DoctorsPAs, NPs and others have done a phenomenal job of banding together and carving out a niche for themselves. They have successfully pushed into doctors' domain and have grabbed market share - and ultimately money - away from physicians.
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Meckel's Diverticulum in Adults: More Common Than You ThinkMeckel's diverticulum is among the most common congenital defects of the gastrointestinal tract. Although often considered a disorder of childhood, it can also be diagnosed in adults. Meckel's diverticulum is often asymptomatic. When patients present with symptoms, diagnosis is complicated because the features are similar to those of many other gastrointestinal conditions, and traditional imaging studies often do not demonstrate an obvious abnormality. Management is evolving, and there is no consensus on the appropriate approach to treatment. This article discusses the pathophysiology, associated complications, and management options for this often-overlooked condition.
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Value of the 6-minute walk test in older patients with chronic heart failureWe assessed the prognostic value of the 6-minute walk test (6-MWT) among 1592 subjects with differing degrees of left ventricular systolic dysfunction (LVSD). We found that the 6-MWT was an independent predictor of mortality, particularly among patients with more than mild LVSD. The 6-MWT provides less prognostic utility in patients with mild or lesser LVSD, however.
