Schizophrenia

Study results reveal that the gene DISC1—shown "to help brain neuronal cells migrate to their correct positions and to help new neurons grow in the developing brain"—directly inhibits GSK3B activity.

New research has discovered how the toxoplasmosis parasite may activate the development of schizophrenia and other bipolar disorders.

The inheritable aspect of schizophrenia may be due to, in large part, structural changes in DNA called copy number variants, not more common genetic variants that have been the focus in previous studies.

Certain antipsychotics, particularly olanzapine and quetiapine, are associated with an increased risk of coronary heart disease (CHD), whereas others—like perphenazine, risperidone and ziprasidone—lead to a decreased risk of CHD, results of a new study in the Journal of Schizophrenia Research show.

Outcomes of a computer-mediated intervention called DIALOG depend on characteristics of the particular patient.