|Podcasts|July 11, 2023

Beyond Glucose Control: The Expanding Role of Incretins in Diabetes and Obesity Management

Author(s)Diana Isaacs, PharmD, BCPS, BCACP, BC-ADM, CDCES, Natalie Bellini, DNP, FNP-BC, BC-ADM, CDCES, Juan Pablo Frias, MD

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In this MEDcast episode, Diana Isaacs, PharmD, BC-ADM, CDCES, and Natalie Bellini, DNP, FNP-BC, interview Dr Juan Frias to explore the mechanism of GLP-1 and GIP agonists in diabetes and weight management and examine key findings from clinical trials for the latest GLP-1/GIP dual agonist.

To watch the video series component of this episode, click here.

1:00 Effect of incretins on blood glucose and body weight

3:24 Evolution of GLP-1 agonists

7:45 Mechanism of tirzepatide- dual GLP-1/GIP agonist

10:35 Overview of SURPASS and SURMOUNT trials for tirzepatide

17:45 Benefits vs. risks of GLP-1 agonists

21:45 Sustainability of weight loss with incretin-based therapies

25:30 Future of metabolic diseases management

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